Gene Report

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Basic Info

Approved Symbol	IMPG1
Previous Symbol	SPACR
Symbol Alias	IPM150, GP147
Approved Name	interphotoreceptor matrix proteoglycan 1
Previous Name	sialoprotein associated with cones and rods
Location	6q14.2-q15
Position	chr6:75921115-76072678, -1
External Links	HGNC: 6055 Entrez Gene: 3617 Ensembl: ENSG00000112706 UCSC: uc003pik.2
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs9343332	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 3)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0007601	visual perception	biological process	TAS[9691169]	15
GO:0005578	proteinaceous extracellular matrix	cellular component	TAS[9691169]	19
GO:0005201	extracellular matrix structural constituent	molecular function	TAS[9691169]	6

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs9343332	chr6:75930833 - 75930833(1)	downstream_gene_variant; intron_variant	1(0/1/0)

rs_ID	Literature-origin SNPs with LD	Location	Functional Annotation
rs2314089		chr6:75934720 - 75934720(1)	intron_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 6	chr6:0-170805979	3 (0/3/0)
6q14-22	chr6:75200000-130000000	1 (0/0/1)
6q14	chr6:75200000-87300000	1 (0/0/1)
6q14.1	chr6:75200000-83200000	2 (0/1/1)
6q13-q14	chr6:69200000-87300000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr6:75921115..76072678 View in gBrowse