Gene Report

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Basic Info

Approved Symbol	POPDC3
Symbol Alias	POP3, MGC22671, bA355M14.1
Approved Name	popeye domain containing 3
Location	6q21
Position	chr6:105158280-105179995, -1
External Links	HGNC: 17649 Entrez Gene: 64208 Ensembl: ENSG00000132429 UCSC: uc003prb.3
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Fan, J., 2010		For gene-based test, P-value = 0.021 in STEP1. nominally significant in STEP1 sample, but not survive Bonferroni correction test.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	NAS[10882522]	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0008150	biological_process	biological process	ND	24
GO:0003674	molecular_function	molecular function	ND	24
GO:0042391	regulation of membrane potential	biological process	IEA	13

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
6q16-q21	chr6:100000000-114200000	1 (0/0/1)
Chr 6	chr6:0-170805979	3 (0/3/0)
6q21	chr6:105000000-114200000	4 (1/2/1)
6q14-22	chr6:75200000-130000000	1 (0/0/1)
6q21-22	chr6:105000000-130000000	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr6:105158280..105179995 View in gBrowse