Gene Report

Basic Info
Approved Symbol PPARD
Symbol Alias NUC1, NUCII, FAAR, NR1C2
Approved Name peroxisome proliferator-activated receptor delta
Previous Name peroxisome proliferative activated receptor, delta
Location 6p21.2
Position chr6:35342558-35428191, 1
External Links HGNC: 9235
Entrez Gene: 5467
Ensembl: ENSG00000112033
UCSC: uc003okm.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Zandi, P. P, 2008 (a) SNP: rs1053046, rs2016520, rs2076166, rs2076167, rs2076168, rs2076169, rs2267665, rs2267666, rs3734254, rs6457816, rs6906237, rs7744392, rs9462082, rs9470001, rs9658100 We found evidence for association of bipolar disorder with PPARD, a gene in the Wnt signaling pathway. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 64)

GO terms by PBA (count: 8)

GO terms by database search (count: 56)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 2)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 3)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 3)

Gene related interactors from protein-protein interactions data in HPRD (count: 22)

Related other genetic factors
Gene related SNPs (count: 37)

Literature-origin SNPs (count: 15)

LD-proxies (count: 22)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

View in gBrowse

Region: chr6:35342558..35428191 View in gBrowse
View in gBrowse