BDgene

BD & SZ shared other variants from cross-disorder studies

Total result: 169

Variant Name Related Gene No. of Studies (Positive/Trend/Negative) for BD No. of Studies for SZ Overlap with SZ
Statistical Results Description Result Category Reference
5HTTLPR SLC6A4 41(12/0/29) 3
no P-value no P-value Although it will be important to extend the present analysi...... Although it will be important to extend the present analysis in a larger sample, our preliminary results suggest that the 5-HTTLPR does not seem to play a major role in the genetics of schizophrenic disorder at least in this group of Brazilian psychiatric patients. More... Negative Mendes de Oliveira, J. R., 1998
allelic P-value = 0.441, genotypic P-value = 0.214, Power c...... allelic P-value = 0.441, genotypic P-value = 0.214, Power calculation GRR=1.46 More... No associations of 5HTTLPR with SCZ was found. No associations of 5HTTLPR with SCZ was found. Negative Ikeda, M., 2006
BDNF Val66Met BDNF 21(11/0/10) 2
Genotype: P-value=0.373 for schizophrenia patients. Alley f...... Genotype: P-value=0.373 for schizophrenia patients. Alley frequency: P-value=0.420 for schizophrenia patients. More... the distribution of the BDNF Val66Met SNP was not different...... the distribution of the BDNF Val66Met SNP was not different between groups. More... Negative Chen, S. L., 2014
schizophrenia vs. control (males and females) -c2 =3.118, d...... schizophrenia vs. control (males and females) -c2 =3.118, df=2, p=0.21 for genotypes, p=0.26 for alleles; schizophrenia vs. control (males) -c 2 =1.468, df=2, p=0.48 for genotypes, p=0.312 for alleles; schizophrenia vs. control (females) -c 2 =2.708, df=2, p=0.258 for genotypes, p=0.482 for alleles. More... The allele and genotype distribution for the patients with ...... The allele and genotype distribution for the patients with schizophrenia or bipolar affective disorder did not differ significantly from controls. When groups were separated according to gender, there was also not any significant difference in allele and genotype distribution. More... Negative Skibinska, M., 2004
SLC6A4 intron2 VNTR SLC6A4 16(4/0/12) 2
allelic P-value = 0.583, genotypic P-value = 0.35, Power ca...... allelic P-value = 0.583, genotypic P-value = 0.35, Power calculation GRR=1.78 More... No associations of 'tagging' marker with SCZ was found. No associations of 'tagging' marker with SCZ was found. Negative Ikeda, M., 2006
Association analysis:TDT, for allele9, T/NT=10/9, P-value =...... Association analysis:TDT, for allele9, T/NT=10/9, P-value = 0.82;for allele10, T/NT=116/125, P-value = 0.56;for allele12, T/NT=128/122, P-value = 0.7 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Dimitrova, A.,2002
MTHFR C677T MTHFR 13(5/0/8) 8
allelic P-value<0.05 for allele C, X2=22.171, OR...... allelic P-value<0.05 for allele C, X2=22.171, OR (CI)=4.677 (2.36-9.28), P-value<0.05 for allele T, X2=14.42, OR (CI)=0.412 (0.26-0.65); genotypic P-value=0.016 for CC, X2=5.829, OR (CI)=2.00 (1.14-3.52), P-value=0.826 for CT, X2=0.048, OR (CI)=0.934 (0.51-1.72), P-value=0.001 for TT, X2=10.667, OR (CI)=0.224 (0.09-0.58) More... There is a significant increase in CC genotype distribution...... There is a significant increase in CC genotype distribution in the control group when compared with the BD and schizophrenia groups. The TT genotype distribution is significantly increased in the schizophrenia group versus the control group. The T allele is significantly prevalent in the BD and schizophrenia groups compared with the control group. The C allele is prevalent in the control group and its prevalence is statistically significant only when compared with the schizophrenia group. More... Positive El-Hadidy, M. A., 2013
T vs. C: P-value Q-test=0.22, Fixed effects OR (95% CI)=1.1...... T vs. C: P-value Q-test=0.22, Fixed effects OR (95% CI)=1.13 [1.04-1.23] , Random effects OR (95% CI)=1.14 [1.03-1.25] in all; P-value Q-test=0.2, Fixed effects OR (95% CI)=1.14 [1.05-1.24], Random effects OR (95% CI)=1.15 [1.04-1.27] in all in HWE; P-value Q-test=0.14, Fixed effects OR (95% CI)=1.13 [1.00-1.27], Random effects OR (95% CI)=1.14 [0.95-1.36] in Caucasians; P-value Q-test=0.1, Fixed effects OR (95% CI)=1.14 [1.01-1.29], Random effects OR (95% CI)=1.17 [0.96-1.41] in Cauc. in HWE; P-value Q-test=0.19, Fixed effects OR (95% CI)=1.15 [1.01-1.31], Random effects OR (95% CI)=1.15 [0.98-1.35] in East Asians; P-value Q-test=0.16, Fixed effects OR (95% CI)=1.15 [0.95-1.38], Random effects OR (95% CI)=1.13 [0.87-1.48] in Men; P-value Q-test=0.42, Fixed effects OR (95% CI)=1.17 [0.96-1.43], Random effects OR (95% CI)=1.17 [0.96-1.43] in Women; TT vs. CC: P-value Q-test=0.2, Fixed effects OR (95% CI)=1.34 [1.12-1.60], Random effects OR (95% CI)=1.34 [1.08-1.67] in all; TT vs. CC: P-value Q-test=0.23, Fixed effects OR (95% CI)=1.37 [1.14-1.64], Random effects OR (95% CI)=1.37 [1.11-1.70] in All in HWE ; P-value Q-test=0.16, Fixed effects OR (95% CI)=1.20 [0.92-1.57] , Random effects OR (95% CI)=1.23 [0.84-1.78] in Caucasians; P-value Q-test=0.16, Fixed effects OR (95% CI)=1.25 [0.95-1.65], Random effects OR (95% CI)=1.30 [0.89-1.89] in Cauc. in HWE; P-value Q-test=0.25, Fixed effects OR (95% CI)=1.40 [1.07-1.83], Random effects OR (95% CI)=1.38 [1.00-1.90] in East Asians; P-value Q-test=0.18, Fixed effects OR (95% CI)=1.27 [0.86-1.90], Random effects OR (95% CI)=1.26 [0.74-2.16] in Men; P-value Q-test=0.62, Fixed effects OR (95% CI)=1.64 [1.02-2.66], Random effects OR (95% CI)=1.65 [1.02-2.66] in Women; TT vs. (TC + CC): P-value Q-test=0.19, Fixed effects OR (95% CI)=1.32 [1.12-1.56], Random effects OR (95% CI)=1.31 [1.07-1.61] in all; P-value Q-test=0.28, Fixed effects OR (95% CI)=1.35 [1.14-1.60], Random effects OR (95% CI)=1.35 [1.11-1.63] in All in HWE; P-value Q-test=0.31, Fixed effects OR (95% CI)=1.10 [0.85-1.41], Random effects OR (95% CI)=1.11 [0.83-1.48] in Caucasians; P-value Q-test=0.4, Fixed effects OR (95% CI)=1.14 [0.88-1.48], Random effects OR (95% CI)=1.15 [0.88-1.49] in Cauc. in HWE; P-value Q-test=0.36, Fixed effects OR (95% CI)=1.45 [1.13-1.85], Random effects OR (95% CI)=1.44 [1.11-1.87] in East Asians; P-value Q-test=0.25, Fixed effects OR (95% CI)=1.19 [0.82-1.72], Random effects OR (95% CI)=1.19 [0.77-1.82] in Men; P-value Q-test=0.35, Fixed effects OR (95% CI)=1.70 [1.07-2.71], Random effects OR (95% CI)=1.71 [1.07-2.71] in Women; (TT + TC) vs. CC: P-value Q-test=0.2, Fixed effects OR (95% CI)=1.21 [1.00-1.25], Random effects OR (95% CI)=1.12 [0.98-1.29] in all; P-value Q-test=0.14, Fixed effects OR (95% CI)=1.12 [1.00-1.25], Random effects OR (95% CI)=1.12 [0.97-1.30] in All in HWE ; P-value Q-test=0.25, Fixed effects OR (95% CI)=1.19 [1.01-1.40] , Random effects OR (95% CI)=1.21 [0.98-1.48] in Caucasians; P-value Q-test=0.15, Fixed effects OR (95% CI)=1.19 [1.01-1.41], Random effects OR (95% CI)=1.23 [0.96-1.56] in Cauc. in HWE; P-value Q-test=0.16, Fixed effects OR (95% CI)=1.09 [0.91-1.30], Random effects OR (95% CI)=1.09 [0.86-1.39] in East Asians; P-value Q-test=0.26, Fixed effects OR (95% CI)=1.19 [0.93-1.53], Random effects OR (95% CI)=1.18 [0.89-1.58] in Men; P-value Q-test=0.12, Fixed effects OR (95% CI)=1.09 [0.85-1.41], Random effects OR (95% CI)=1.14 [0.75-1.74] in Women. More... The main analysis for investigating the association of the ...... The main analysis for investigating the association of the C677T allele T and the risk of developing schizophrenia relative to the allele C showed lack of heterogeneity between the 10 studies; the FEs pooled OR was marginally significant. In subgroup analysis, there was moderate heterogeneity between the studies performed in Caucasians and in east Asians. The REs and FEs pooled ORs were not significant in Caucasians and in Asians. The genotype differences for the homozygotes revealed either absent or moderate heterogeneity and a significant association in the main analysis. In Caucasians, the association, however, was not significant whereas in east Asians the opposite pattern was detected. The recessive model for allele T produced the same pattern of genotypic association as found for the homozygote frequencies, and found no evidence for heterogeneity in Caucasians and in east Asians. The dominant model for the effect of Tallele in the main analysis and in Caucasians showed marginal (or no) association, and for the east Asians lack of significant association. The sensitivity analysis did not alter the pattern of results. Regarding sex, in female participants, there is indication of significant association for the difference in homozygotes (marginal) and the differences of genotypes supporting a recessive model. More... Negative Zintzaras, E., 2006
HTR2A C102T HTR2A 8(0/0/8) 2
Allelic P-value = 0.616 Allelic P-value = 0.616 In the schizophrenia sample, the analysis of the HTR2A T102...... In the schizophrenia sample, the analysis of the HTR2A T102C SNP did not reveal preferential transmission for either allele overall More... Negative De Luca, V., 2007
Fisher's Exact Test:for SZ, genotypes:P-value > 0.05; allel...... Fisher's Exact Test:for SZ, genotypes:P-value > 0.05; alleles:P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Abdolmaleky, H. M.,2011
DRD4 exon3 VNTR DRD4 8(1/0/7) 1
Association analysis:chi sauqre test, all P-value > 0.05 Association analysis:chi sauqre test, all P-value > 0.05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Serretti, A.,2001(b)
TPH1 A218C TPH1 6(2/0/4) 1
Association analysis:chi sauqre test, P-value > 0.05 Association analysis:chi sauqre test, P-value > 0.05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Serretti, A.,2001(a)
DRD1 -48A/G DRD1 5(3/0/2) 1
Schizophrenia vs. control: genotypic P-value = 0.49, alleli...... Schizophrenia vs. control: genotypic P-value = 0.49, allelic P-value = 0.41, X2=1.427, d.f.=2 More... The genotype distribution and allele frequency in patients ...... The genotype distribution and allele frequency in patients with schizophrenia did not differ significantly from controls. More... Negative Dmitrzak-Weglarz, M., 2006
DRD2 S311C DRD2 5(0/0/5) 2
Association analysis:chi sauqre test, chi square= 4.29; df ...... Association analysis:chi sauqre test, chi square= 4.29; df = 1; P-value = 0.038 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Serretti, A.,2000(a)
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Sasaki, T.,1996
SERT VNTR SLC6A4 4(2/0/2) 2
chi square tests:allele 12, P-value = 0.007 chi square tests:allele 12, P-value = 0.007 Significant differences were found in SZ groups. Significant differences were found in SZ groups. Positive Liu, W,1999
chi square test:allele 12, chi 2 p = 0.08 chi square test:allele 12, chi 2 p = 0.08 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Collier, D. A.,1996
ACE insertion/deletion ACE 4(2/0/2) 1
chi square test:SZ: P-value < 89 for genotype DD/(ID+II);P-...... chi square test:SZ: P-value < 89 for genotype DD/(ID+II);P-value < 0.28 for allele More... There is no significant difference in the frequencies of th...... There is no significant difference in the frequencies of the allele and the genotype between the controls and schizophrenics. More... Negative Arinami, T.,1996
KCNN3 exon 1 CAG-repeat KCNN3 4(0/0/4) 3
Association analysis:chi sauqre test, chi square=0.0, d.f.=...... Association analysis:chi sauqre test, chi square=0.0, d.f.=2, P-value = 0.99 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ujike, H.,2001
Association analysis:chi sauqre test, chi square=8.35, df=8...... Association analysis:chi sauqre test, chi square=8.35, df=8, P-value = 0.40 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Saleem, Q.,2000
MTHFR A1298C MTHFR 4(3/0/1) 3
Fisher exact test, P-value = 0.0151, OR (95% CI)=2.694(1.20...... Fisher exact test, P-value = 0.0151, OR (95% CI)=2.694(1.207-6.0130), chi-square P-value = 0.0123 for CC vs AC & AA genotypes in total patients with SZ; Fisher exact test, P-value = 0.1158, OR (95% CI)=0.745(0.518-1.070), chi-square P-value = 0.1107 for CC & AC vs AA in total patients with SZ; Fisher exact test, P-value = 0.1671, OR (95% CI)=2.968(0.724-12.163), chi-square P-value = 0.1144 for CC vs AC & AA genotypes in females patients with SZ; Fisher exact test, P-value = 0.1802, OR (95% CI)=0.687(0.406-1.162), chi-square P-value = 0.1604 for CC & AC vs AA in females patients with SZ; Fisher exact test, P-value = 0.0764, OR (95% CI)=2.654(0.993-7.091), chi-square P-value = 0.0446 for CC vs AC & AA genotypes in males patients with SZ; Fisher exact test, P-value = 0.3724, OR (95% CI)=0.794(0.481-1.314), chi-square P-value = 0.3695 for CC & AC vs AA in males patients with SZ; chi-square P-value = 0.9617, OR (95% CI)=0.988 (0.610-1.602) for CC/AC vs CC/AA; P-value = 0.0423, OR (95% CI)=2.929 (0.998-8.595) for CC/CC vs CC/AA; P-value = 0.7257, OR (95% CI)=1.1 (0.645-1.879) for CT/AA vs CC/AA; P-value = 0.0002, OR (95% CI)=3.221 (1.711-6.067) for CT/AC vs CC/AA; P-value = 0.3475, OR (95% CI)=1.952 (0.473-8.067) for CT/CC vs CC/AA; P-value = 0.0017, OR (95% CI)=4.184 (1.623-10.787) for TT/AA vs CC/AA; P-value = 0.1545, OR (95% CI)=0 for TT/AC vs CC/AA; P-value = 0.0062, OR (95% CI)= for TT/CC vs CC/AA in SZ patients More... The results confirm association of SZ with the 1p36.3 MTHFR...... The results confirm association of SZ with the 1p36.3 MTHFR locus. The frequency of heterozygous 1298CA genotype was higher in patients as compared to controls but was not significantly different. Gender classification of patients did not indicate association of homozygous 1298CC genotype with either schizophrenia in the female nor male patients. More... Positive Kempisty, B., 2007 (a)
Meta analysis:Model1, fixed OR(95%CI)=1.08(0.93-1.26), I Meta analysis:Model1, fixed OR(95%CI)=1.08(0.93-1.26), I2%=31.4, random OR(95%CI)=1.12(0.92-1.37);Model2, fixed OR(95%CI)=1.08(0.98-1.19), I2%=61.4, random OR(95%CI)=1.07(0.90-1.26);Model3, fixed OR(95%CI)=1.1(0.93-1.29), I2%=37.6, random OR(95%CI)=1.13(0.91-1.41);Model4, fixed OR(95%CI)=1.12(0.94-1.33), I2%=22.2, random OR(95%CI)=1.16(0.94-1.43);Model5, fixed OR(95%CI)=1.06(0.99-1.15), I2%=61.1, random OR(95%CI)=1.07(0.94-1.21) More... Diagnosis of SZ was not significantly associated with MTHFR...... Diagnosis of SZ was not significantly associated with MTHFR A1298C. More... Negative Peerbooms, O. L.,2011
BDNF (GT)n BDNF 3(2/0/1) 1
Allele distribution:in Bonn sample, for Schizophrenia, glob...... Allele distribution:in Bonn sample, for Schizophrenia, global P-value = 0.350 More... No significant association was observed. No significant association was observed. Negative Schumacher, J.,2005
TCF4 CTG18.1 TCF4 3(1/0/2) 1
Association analysis:X2 test, P-value = 0.26 Association analysis:X2 test, P-value = 0.26 No significant association was observed. No significant association was observed. Negative McInnis, M. G.,2000
MAOA T941G MAOA 3(2/0/1) 1
no P-value was given no P-value was given No significant differences in the allele or genotype distri...... No significant differences in the allele or genotype distribution were observed between the control group and any disease group. More... Negative Sasaki, T., 1998
ERDA1 microsatellite ERDA1 3(0/0/3) 1
chi square test:SCZ: P = 0.05 chi square test:SCZ: P = 0.05 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Vincent, J. B.,1999(b)
NRG1 SNP8NRG241930 NRG1 3(0/0/3) 1
Individual P-value = 0.6237 for SCZ , Individual P-value = ...... Individual P-value = 0.6237 for SCZ , Individual P-value = 0.8147 for SCZ and BP More... Negative Thomson, P. A., 2007
NRG1 SNP8NRG243177 NRG1 3(0/0/3) 1
Individual P-value = 0.8945 for SCZ , Individual P-value = ...... Individual P-value = 0.8945 for SCZ , Individual P-value = 0.5341 for SCZ and BP More... Negative Thomson, P. A., 2007
GPR50 delta502-505 GPR50 3(1/0/2) 1
Single marker association:for SCZ, allele P-value = 0.12(al...... Single marker association:for SCZ, allele P-value = 0.12(all), P-value = 0.15(male), P-value = 0.92(female) More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(b)
GSK3B -1727A/T GSK3B 3(0/0/3) 1
allelic P-value = 0.86, genotypic P-value = 1.00 for SZ pat...... allelic P-value = 0.86, genotypic P-value = 1.00 for SZ patients, allelic P-value = 0.82, genotypic P-value = 0.34 for BD and SZ patients More... Whether allele- or genotype-wise, no evidence of associatio...... Whether allele- or genotype-wise, no evidence of association with either samples of schizophrenia and bipolar disorder could be detected. Same results were obtained when the combined samples of schizophrenia and bipolar disorder were compared to healthy controls. When the samples were compared by each sex, there was also no evidence of association between patients and controls. More... Negative Lee, K. Y., 2006 (b)
GSK3B -50T/C GSK3B 3(0/0/3) 1
allelic P-value = 0.94, genotypic P-value = 0.76 for SZ pat...... allelic P-value = 0.94, genotypic P-value = 0.76 for SZ patients, allelic P-value = 0.62, genotypic P-value = 0.53 for BD and SZ patients More... Whether allele- or genotype-wise, no evidence of associatio...... Whether allele- or genotype-wise, no evidence of association with either samples of schizophrenia and bipolar disorder could be detected. Same results were obtained when the combined samples of schizophrenia and bipolar disorder were compared to healthy controls. When the samples were compared by each sex, there was also no evidence of association between patients and controls. More... Negative Lee, K. Y., 2006 (b)
RGS4 SNP1 RGS4 2(0/0/2) 1
Family-based analysis:TDT:X2=1.2, P-value = 0.27...... Family-based analysis:TDT:X2=1.2, P-value = 0.274 in SZ More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Cordeiro, Q.,2005
HTR6 267C/T HTR6 2(1/0/1) 1
Assocaition analysis:Fisher's exact test, two-tailed, genot...... Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.274, allele P-value = 0.249 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Vogt, I. R.,2000
IL1RN intron 2 VNTR IL1RN 2(1/0/1) 1
Association analysis:chi square test, Schizophrenia v contr...... Association analysis:chi square test, Schizophrenia v controls: allele: chi square= 0.33, P-value = 0.84; genotype: chi square= 1.62, P-value = 0.65. More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Papiol, S.,2004
IMPA2 -185A>G IMPA2 2(0/0/2) 1
Fisher's exact test, allelic P-value = 0.507, genotypic P-v...... Fisher's exact test, allelic P-value = 0.507, genotypic P-value = 0.797 More... Negative Ohnishi, T., 2007
IMPA2 -207T>C IMPA2 2(2/0/0) 1
Fisher's exact test, allelic P-value = 0.207, genotypic P-v...... Fisher's exact test, allelic P-value = 0.207, genotypic P-value = 0.294 More... Negative Ohnishi, T., 2007
TNF -G308A TNF 2(1/0/1) 1
Association analysis:chi square test, X2=12.8, 2...... Association analysis:chi square test, X2=12.8, 2 df, P-value = 0.001 for genotype, P-value = 0.01 for allele. More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Meira-Lima, I.,2003(b)
NOS1 promoter VNTR NOS1 2(0/0/2) 2
P-value = 0.355, X2=2.07, df=2 in unsystematic S...... P-value = 0.355, X2=2.07, df=2 in unsystematic SCZ, P-value = 0.429, X2=1.70, df=2 in systematic SCZ, P-value = 0.353, X2=2.08, df=2 in total sample with SCZ More... schizophrenic patients did not differ significantly from co...... schizophrenic patients did not differ significantly from controls in dichotomized VNTR1 genotype frequencies; there was no significant effect of VNTR1 with regard to the two SCZ subgroups. More... Negative Reif, A., 2006 (a)
Association analysis:X2=2.9, genotypic P-value =...... Association analysis:X2=2.9, genotypic P-value = 0.58 More... No significant association was observed. No significant association was observed. Negative Silberberg, G.,2010
NRG1 SNP8NRG221533 NRG1 2(0/0/2) 1
Individual P-value = 0.7189 for SCZ , Individual P-value = ...... Individual P-value = 0.7189 for SCZ , Individual P-value = 0.7929 for SCZ and BP More... Negative Thomson, P. A., 2007
GRIN2B -200G/T GRIN2B 2(0/0/2) 1
P-value (corrected)=0.0003, X2=17.974, df=2 of a...... P-value (corrected)=0.0003, X2=17.974, df=2 of allele frequencies and association analysis in the schizophrenia case-control sample; case-control P-value < 0.0001, corrected for multiple testing P-value = 0.0003, case-control+triad P-value = 0.0009 of G/G genotype for the combined family and case-control schizophrenia samples; case-control P-value < 0.0001, corrected for multiple testing P-value = 0.0003, case-control+triad P-value = 0.0027 of G allele for the combined family and case-control schizophrenia samples; FBAT P-value = 0.44, z=0.775 in SCZ triads More... For the T-200G polymorphism, there was a statistically sign...... For the T-200G polymorphism, there was a statistically significant association between the G allele with schizophrenia in the case-control sample; for the G/G genotype as well as for the presence of the G allele. The result is still statistically significant after correcting for multiple testing. The nuclear families were tested for association using FBAT, showing no preferential transmission of either allele. Combining the z scores from the nuclear families and the case-control, we obtained an overall statistically significant result. More... Positive Martucci, L., 2006
PRODH-2026 PRODH 1(0/0/1) 1
Armitage trend test:P-value(odds ratio)=0.346(1.27) for SZ Armitage trend test:P-value(odds ratio)=0.346(1.27) for SZ No significant associations were found in SZ. No significant associations were found in SZ. Negative Abou Jamra, R.,2005(a)
PRODH exon12 A472T PRODH 1(0/0/1) 1
Association study:P-value (genotypic)=0.89, P-value (alleli...... Association study:P-value (genotypic)=0.89, P-value (allelic)=0.9 for SZ. More... No significant association was observed. No significant association was observed. Negative Jacquet, H.,2005
PRODH exon12 R431H PRODH 1(0/0/1) 1
Association study:P-value (genotypic)=0.68, P-value (alleli...... Association study:P-value (genotypic)=0.68, P-value (allelic)=0.54 for SZ. More... No significant association was observed. No significant association was observed. Negative Jacquet, H.,2005
22CH3 CAG repeat 1(1/0/0) 1
Association analysis:allele frequencies, X2 = 5....... Association analysis:allele frequencies, X2 = 5.19, df = 1, P-value < 0.02;genotype frequencies:X2 = 5.69, df = 2, P-value = 0.06 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Saleem, Q.,2001
RGS4 SNP18 RGS4 1(0/0/1) 1
Family-based analysis:TDT:X2=3.6, P-value = 0.05...... Family-based analysis:TDT:X2=3.6, P-value = 0.057 in SZ More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Cordeiro, Q.,2005
RGS4 SNP4 RGS4 1(0/0/1) 1
Family-based analysis:TDT:X2=2.31, P-value = 0.1...... Family-based analysis:TDT:X2=2.31, P-value = 0.128 in SZ More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Cordeiro, Q.,2005
RGS4 SNP7 RGS4 1(1/0/0) 1
Family-based analysis:TDT:X2=1.2, P-value = 0.27...... Family-based analysis:TDT:X2=1.2, P-value = 0.274 in SZ More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Cordeiro, Q.,2005
rs1599988 mtDNA 1(1/0/0) 1
MDS covariates:BD vs.SZ, OR=1.712, P-value = 0.014 MDS covariates:BD vs.SZ, OR=1.712, P-value = 0.014 Significant association was observed in SZ. Significant association was observed in SZ. Positive Sequeira, A.,2012
rs2853515 mtDNA 1(1/0/0) 1
MDS covariates:BD vs.SZ, OR=1.762, P-value = 0.021 MDS covariates:BD vs.SZ, OR=1.762, P-value = 0.021 Significant association was observed in SZ. Significant association was observed in SZ. Positive Sequeira, A.,2012
rs3937033 mtDNA 1(1/0/0) 1
MDS covariates:BD vs.SZ, OR=1.112, P-value = 0.043 MDS covariates:BD vs.SZ, OR=1.112, P-value = 0.043 Significant association was observed in SZ. Significant association was observed in SZ. Positive Sequeira, A.,2012
AADC exon 1 T>A DDC 1(0/0/1) 1
Association analysis:allele frequencies, X2 = 0....... Association analysis:allele frequencies, X2 = 0.37, 1 df, OR 1.12, 95% CI = 0.75-1.59, P-value > 0.05;genotypes, X2 = 0.41, 2 df, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Speight, G.,2000
rs769404 GAD1 1(0/0/1) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.28, P-value(genotype)=0.48 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
ABCA13 exon33 H3609P ABCA13 1(0/0/1) 1
Fisher's exact test:P-value = 0.334 , Odds Ratio=1.37 in SC...... Fisher's exact test:P-value = 0.334 , Odds Ratio=1.37 in SCZ More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Knight, H. M.,2009
ABCA13 exon40 T4031A ABCA13 1(1/0/0) 1
Fisher's exact test:P-value = 0.334 , Odds Ratio=1.37 in SC...... Fisher's exact test:P-value = 0.334 , Odds Ratio=1.37 in SCZ More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Knight, H. M.,2009
ABCA13 exon52 R4590W ABCA13 1(0/0/1) 1
Fisher's exact test:P-value = 0.38, Odds Ratio=1.5 in SCZ Fisher's exact test:P-value = 0.38, Odds Ratio=1.5 in SCZ No significant associations were found in SZ. No significant associations were found in SZ. Negative Knight, H. M.,2009
ABCA13 exon52 T4550A ABCA13 1(1/0/0) 1
Fisher's exact test:P-value = 0.054 , Odds Ratio=3.29 in SC...... Fisher's exact test:P-value = 0.054 , Odds Ratio=3.29 in SCZ More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Knight, H. M.,2009
ABCA13 exon54 R4728X ABCA13 1(0/0/1) 1
Fisher's exact test:P-value = 0.370, Odds Ratio=1.51 in SCZ Fisher's exact test:P-value = 0.370, Odds Ratio=1.51 in SCZ No significant associations were found in SZ. No significant associations were found in SZ. Negative Knight, H. M.,2009
ABCA13 exon57 R4843C ABCA13 1(0/0/1) 1
Fisher's exact test:P-value = 0.047, Odds Ratio=2.54 in SCZ...... Fisher's exact test:P-value = 0.047, Odds Ratio=2.54 in SCZ More... Significant associations were found in SZ. Significant associations were found in SZ. Positive Knight, H. M.,2009
SEF2-1B 1(0/0/1) 1
chi square test:SCZ: P = 0.61 chi square test:SCZ: P = 0.61 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Vincent, J. B.,1999(b)
SLC12A6 32416574(G/A) SLC12A6 1(1/0/0) 1
For Schizophrenia vs. controls:Allele, Exact test, P-value ...... For Schizophrenia vs. controls:Allele, Exact test, P-value = 0.0678, Odds ratio=4.10 (0.91-18.46);genotype, Exact test, P-value = 0.0671, Odds ratio=4.12 (0.92-18.86) More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Meyer, J.,2005
SLC12A6 32418760(G/A) SLC12A6 1(1/0/0) 1
For Schizophrenia vs. controls:Allele, Exact test, P-value ...... For Schizophrenia vs. controls:Allele, Exact test, P-value = 0.0596, Odds ratio=3.54 (0.94-13.31) ;genotype, Exact test, P-value = 0.0586, Odds ratio=3.60 (0.95-13.65) More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Meyer, J.,2005
SLC12A6 IVS4+1008ins(T)/del(T) SLC12A6 1(1/0/0) 1
For Schizophrenia vs. controls:Allele, X2 test, ...... For Schizophrenia vs. controls:Allele, X2 test, 1 d.f., X2=1.90, P-value = 0.1680, 1.55 (0.83-2.91);genotype, , Armitage trend test, Z=-1.42, P-value = 0.1546, Odds ratio=1.60 (0.83-3.07) More... No significant associations were found in SZ. No significant associations were found in SZ. Negative Meyer, J.,2005
SLC1A4-11 SLC1A4 1(0/0/1) 1
no P-value no P-value Allele and haplotype frequencies did not differ between cas...... Allele and haplotype frequencies did not differ between cases and controls. More... Negative Skowronek, M. H., 2006
HTR3A exon1 Leu10Leu HTR3A 1(0/0/1) 1
Association analysis:chi square tests, P-value = 0.389 Association analysis:chi square tests, P-value = 0.389 No significant association was observed in SZ. No significant association was observed in SZ. Negative Niesler, B.,2001(b)
HTR3A exon3 A(+7 IVS3)C HTR3A 1(0/0/1) 1
Association analysis:chi square tests, P-value = 0.785 Association analysis:chi square tests, P-value = 0.785 No significant association was observed in SZ. No significant association was observed in SZ. Negative Niesler, B.,2001(b)
HTR3A exon6 Leu192Leu HTR3A 1(0/0/1) 1
Association analysis:chi square tests, P-value = 1 Association analysis:chi square tests, P-value = 1 No significant association was observed in SZ. No significant association was observed in SZ. Negative Niesler, B.,2001(b)
ADCYAP1 IVS3 37A/T ADCYAP1 1(0/0/1) 1
Association analysis:Fisher's exact test (two-tailed), alle...... Association analysis:Fisher's exact test (two-tailed), allele P-value = 1.00 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ishiguro, H.,2001
HTR3A exon7 Lys277Lys HTR3A 1(0/0/1) 1
Association analysis:chi square tests, P-value = 0.482 Association analysis:chi square tests, P-value = 0.482 No significant association was observed in SZ. No significant association was observed in SZ. Negative Niesler, B.,2001(b)
HTR3A exon8 Arg344His HTR3A 1(0/0/1) 1
Association analysis:chi square tests, P-value = 1 Association analysis:chi square tests, P-value = 1 No significant association was observed in SZ. No significant association was observed in SZ. Negative Niesler, B.,2001(b)
SLC6A3 3'UTR VNTR SLC6A3 1(0/0/1) 1
Association analysis:allele 9 repeat, T/NT=78/84, P-value =...... Association analysis:allele 9 repeat, T/NT=78/84, P-value = 0.64;allele 10 repeat, T/NT=85/81, P-value = 0.76 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Georgieva, L.,2002
HTR3A exon9 Leu459Leu HTR3A 1(0/0/1) 1
Association analysis:chi square tests, P-value = 0.055 Association analysis:chi square tests, P-value = 0.055 No significant association was observed in SZ. No significant association was observed in SZ. Negative Niesler, B.,2001(b)
HTR3A exon9 Pro391Arg HTR3A 1(0/0/1) 1
Association analysis:chi square tests, P-value = 0.055 Association analysis:chi square tests, P-value = 0.055 No significant association was observed in SZ. No significant association was observed in SZ. Negative Niesler, B.,2001(b)
HTR3B 386A>C (Tyr129Ser) HTR3B 1(1/0/0) 1
Genotypic P-value = 0.87. OR (95% CI)=1.07 (0.55-2.1); all...... Genotypic P-value = 0.87. OR (95% CI)=1.07 (0.55-2.1); allelic P-value = 0.87, OR (95% CI)=1.05 (0.59-1.87) in the schizophrenia patients (n=78) compared with controls (n=62) More... Most of the tested SNPs did not reach statistical significa...... Most of the tested SNPs did not reach statistical significance since there was no outstanding difference in allele and genotype distributions between the sample of patients with BPAD or SZ and the control sample More... Negative Frank, B., 2004
HTR3B 547G>A (Val183Ile) HTR3B 1(1/0/0) 1
Genotypic P-value = 0.63. OR (95% CI)=2.44 (0.25-24.05); a...... Genotypic P-value = 0.63. OR (95% CI)=2.44 (0.25-24.05); allelic P-value = 0.63, OR (95% CI)=2.41 (0.25-23.48) in the schizophrenia patients (n=78) compared with controls (n=62) More... Most of the tested SNPs did not reach statistical significa...... Most of the tested SNPs did not reach statistical significance since there was no outstanding difference in allele and genotype distributions between the sample of patients with BPAD or SZ and the control sample More... Negative Frank, B., 2004
HTR3B 5'UTR -102delAAG HTR3B 1(1/0/0) 1
Genotypic P-value = 0.22. OR (95% CI)=0.58 (0.26-1.29); al...... Genotypic P-value = 0.22. OR (95% CI)=0.58 (0.26-1.29); allelic P-value = 0.21, OR (95% CI)=0.62 (0.29-1.31) in the schizophrenia patients (n=78) compared with controls (n=62). More... Most of the tested SNPs did not reach statistical significa...... Most of the tested SNPs did not reach statistical significance since there was no outstanding difference in allele and genotype distributions between the sample of patients with BPAD or SZ and the control sample More... Negative Frank, B., 2004
HTR3B IVS4+11C>T HTR3B 1(0/0/1) 1
Genotypic P-value = 0.64. OR (95% CI)=1.35 (0.52-3.5); all...... Genotypic P-value = 0.64. OR (95% CI)=1.35 (0.52-3.5); allelic P-value = 0.55, OR (95% CI)=1.32 (0.53-3.29) in the schizophrenia patients (n=78) compared with controls (n=62) More... Most of the tested SNPs did not reach statistical significa...... Most of the tested SNPs did not reach statistical significance since there was no outstanding difference in allele and genotype distributions between the sample of patients with BPAD or SZ and the control sample More... Negative Frank, B., 2004
MTHFR exon 4 C677T MTHFR 1(1/0/0) 1
All studies: T vs. C: OR=1.15, 95%CI=1.07-1.23, P-value=<0....... All studies: T vs. C: OR=1.15, 95%CI=1.07-1.23, P-value=<0.001; TT + CT vs. CC: OR=1.14, 95%CI=1.05-1.24, P-value=0.001; TT vs. CT + CC: OR=1.34, 95%CI=1.18-1.53, P-value=<0.001; TT vs. CC: OR=1.33, 95%CI=1.15-1.54, P-value=<0.001. white: T vs. C: OR=1.07, 95%CI=0.98-1.16, P-value=0.141; TT + CT vs. CC: OR=1.07, 95%CI=0.96-1.18, P-value=0.217; TT vs. CT + CC: OR=1.13, 95%CI=0.95-1.36, P-value=0.17; TT vs. CC: OR=1.15, 95%CI=0.94-1.40, P-value=0.173. Asian: T vs. C: OR=1.21, 95%CI=1.08-1.34, P-value=0.001; TT + CT vs. CC: OR=1.22, 95%CI=1.07-1.38, P-value=0.003; TT vs. CT + CC: OR=1.50, 95%CI=1.26-1.78, P-value=<0.001; TT vs. CC: OR=1.46, 95%CI=1.19-1.78, P-value=<0.001. African: T vs. C: OR=2.14, 95%CI=1.42-3.23, P-value=<0.001; TT + CT vs. CC: OR=1.85, 95%CI=1.10-3.09, P-value=0.02; TT vs. CT + CC: OR=4.28, 95%CI=1.76-10.29, P-value=0.001; TT vs. CC: OR=4.67, 95%CI=1.89-11.57, P-value=0.001 More... Meta-analysis showed that MTHFR C677T was significantly ass...... Meta-analysis showed that MTHFR C677T was significantly associated with SZ. More... Positive Hu C.Y., 2014
HTR3B IVS4+12G>A HTR3B 1(0/0/1) 1
Genotypic P-value = 0.34. OR (95% CI)=1.54 (0.78-3.07); al...... Genotypic P-value = 0.34. OR (95% CI)=1.54 (0.78-3.07); allelic P-value = 0.16, OR (95% CI)=1.42 (0.87-2.33) in the schizophrenia patients (n=78) compared with controls (n=62). More... Most of the tested SNPs did not reach statistical significa...... Most of the tested SNPs did not reach statistical significance since there was no outstanding difference in allele and genotype distributions between the sample of patients with BPAD or SZ and the control sample More... Negative Frank, B., 2004
MTHFR exon 7 A1298C MTHFR 1(1/0/0) 1
All studies: C vs. A: OR=1.08, 95%CI=0.99-1.18, P-value=0.0...... All studies: C vs. A: OR=1.08, 95%CI=0.99-1.18, P-value=0.081; CC + AC vs. AA: OR=1.10, 95%CI=1.00-1.22, P-value=0.049; CC vs. AC + AA: OR=1.13, 95%CI=0.95-1.35, P-value=0.166; CC vs. AA: OR=1.18, 95%CI=0.97-1.44, P-value=0.104. white: C vs. A: OR=1.07, 95%CI=0.96-1.19, P-value=0.218; CC + AC vs. AA: OR=1.08, 95%CI=0.95-1.23, P-value=0.217; CC vs. AC + AA: OR=1.13, 95%CI=0.89-1.43, P-value=0.313; CC vs. AA: OR=1.17, 95%CI=0.90-1.51, P-value=0.239. Asian: C vs. A: OR=1.10, 95%CI=0.94-1.29, P-value=0.253; CC + AC vs. AA: OR=1.14, 95%CI=0.96-1.35, P-value=0.136; CC vs. AC + AA: OR=1.15, 95%CI=0.86-1.54, P-value=0.342; CC vs. AA: OR=1.23, 95%CI=0.86-1.76, P-value=0.265 More... MTHFR A1298C was significant associated with SZ. MTHFR A1298C was significant associated with SZ. Positive Hu C.Y., 2014
HTR3B IVS6+72A>G HTR3B 1(0/0/1) 1
Genotypic P-value = 0.46. OR (95% CI)=1.4 (0.68-2.9); alle...... Genotypic P-value = 0.46. OR (95% CI)=1.4 (0.68-2.9); allelic P-value = 0.41, OR (95% CI)=1.32 (0.68-2.55) in the schizophrenia patients (n=78) compared with controls (n=62) More... Most of the tested SNPs did not reach statistical significa...... Most of the tested SNPs did not reach statistical significance since there was no outstanding difference in allele and genotype distributions between the sample of patients with BPAD or SZ and the control sample More... Negative Frank, B., 2004
HTR4 IVS1+15T/C HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.28, allele P-value = 0.62, OR=0.8OR(95%CI)=0.3-2.1 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
HTR4 IVS3+63C/T HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.65, allele P-value = 0.42, OR=1.3OR(95%CI)=0.8-2.2 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
HTR4 IVS3+6G/A HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.97, allele P-value = 0.81, OR=1.1OR(95%CI)=0.7-1.7 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
HTR4 IVS4+36T/C HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.47, allele P-value = 0.66, OR=1.1OR(95%CI)=0.7-1.7 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
alpha8-alpha10 del 5q31-linked PCDH family 1(0/0/1) 1
SZ allele frequency X2=0.02, P-value = 1.00 SZ allele frequency X2=0.02, P-value = 1.00 Negative Lachman, H. M., 2008
HTR4 SVRSNP1 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.48, allele P-value = 0.28, OR=1.2OR(95%CI)=0.9-1.7;Transmission disequilibrium test:Schizophrenia(RIKEN families):T/NT=43/50, chi square=0.53, P-value = 0.47 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
HTR4 SVRSNP2 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.55, allele P-value = 1, OR=1OR(95%CI)=0.6-1.7 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
SLC6A5 AC-tandem-repeat SLC6A5 1(0/0/1) 1
data not shown data not shown In the single-marker analysis, none of the analyzed variant...... In the single-marker analysis, none of the analyzed variants revealed a significant association with disease. More... Negative Jamra, R. A., 2006 (b)
HTR4 SVRSNP3 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.19, allele P-value = 0.12, OR=1.4OR(95%CI)=0.9-2.1 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
HTR4 SVRSNP4 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.34, allele P-value = 0.16, OR=1.3OR(95%CI)=0.9-2.0;Transmission disequilibrium test:Schizophrenia(RIKEN families):T/NT=34/45, chi square=1.53, P-value = 0.22 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Ohtsuki, T.,2002
SNAP29 exon1 56T>C SNAP29 1(0/0/1) 1
Association analysis:the Pearson X2 test, CONT v...... Association analysis:the Pearson X2 test, CONT vs SZ, X2= 3.74, allele P-value = 0.05; X2= 4.71, genotype P-value = 0.095; More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Saito, T.,2001
SNAP29 exon1 92A>G SNAP29 1(0/0/1) 1
Association analysis:the Pearson X2 test, CONT v...... Association analysis:the Pearson X2 test, CONT vs SZ, X2= 4.56, allele P-value = 0.03; X2=5.17, genotype P-value = 0.08; More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Saito, T.,2001
SNAP29 promoter -849G>A SNAP29 1(0/0/1) 1
Association analysis:the Pearson X2 test, CONT v...... Association analysis:the Pearson X2 test, CONT vs SZ, X2= 5.57, allele P-value = 0.018; X2=9.49, genotype P-value = 0.009; More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Saito, T.,2001
HTR6 126G/T HTR6 1(0/0/1) 1
Assocaition analysis:Fisher's exact test, two-tailed, genot...... Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.485, allele P-value = 0.497 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Vogt, I. R.,2000
HTR6 873+128A/C HTR6 1(1/0/0) 1
Assocaition analysis:Fisher's exact test, two-tailed, genot...... Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.119, allele P-value = 0.114 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Vogt, I. R.,2000
MIR137/MIR2682 Chr1:98515539 A/T MIR137, MIR2682 1(1/0/0) 1
Fisher P-value=0.0007 Fisher P-value=0.0007 In the combined case samples, the association of 1:g.985155...... In the combined case samples, the association of 1:g.98515539A>T with SZ was 0.0007. Significant association was observed. More... Positive Duan, J., 2014
SYNGR1 exon3 Ser97Ser SYNGR1 1(1/0/0) 1
Fisher's exact test:allele P-value = 0.7, chi-square test:g...... Fisher's exact test:allele P-value = 0.7, chi-square test:genotype P-value = 0.7 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
SYNGR1 exon6 Asn(ins/del) SYNGR1 1(0/0/1) 1
Fisher's exact test:allele P-value = 0.6, chi-square test:g...... Fisher's exact test:allele P-value = 0.6, chi-square test:genotype P-value = 0.9 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
SLC1A2 Chr1:35344202 G/T SLC1A2 1(0/0/1) 1
NA NA None of the variants were found to be associated with SZ or...... None of the variants were found to be associated with SZ or with the two diseases combined. More... Negative Fiorentino, A., 2014
SLC1A2 Chr1:35339061 C/T SLC1A2 1(0/0/1) 1
SZ: P-value=1.00 SZ: P-value=1.00 None of the variants were found to be associated with SZ or...... None of the variants were found to be associated with SZ or with the two diseases combined. More... Negative Fiorentino, A., 2014
SLC1A2 Chr1:35282452 C/T SLC1A2 1(0/0/1) 1
SZ: P-value=0.358 SZ: P-value=0.358 None of the variants were found to be associated with SZ or...... None of the variants were found to be associated with SZ or with the two diseases combined. More... Negative Fiorentino, A., 2014
IMPA2 -708G>A IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.659, genotypic P-v...... Fisher's exact test, allelic P-value = 0.659, genotypic P-value = 0.204 More... Negative Ohnishi, T., 2007
TBX1 v14186 TBX1 1(0/0/1) 1
X2= 1.080, P-value = 0.299 for schizophrenia wh...... X2= 1.080, P-value = 0.299 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
IMPA2 IVS1-15G>A IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.297, genotypic P-v...... Fisher's exact test, allelic P-value = 0.297, genotypic P-value = 0.038 More... Modest nominal genotypic association of with schizophrenia ...... Modest nominal genotypic association of with schizophrenia was detected. More... Positive Ohnishi, T., 2007
IMPA2 IVS5+13-14InsA IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.183, genotypic P-v...... Fisher's exact test, allelic P-value = 0.183, genotypic P-value = 0.365 More... Negative Ohnishi, T., 2007
CHRFAM7A 2bp deletion CHRFAM7A 1(0/0/1) 1
P-value = 0.9, X2=0.19, 2 df for schizophrenia v...... P-value = 0.9, X2=0.19, 2 df for schizophrenia versus controls, 2bp deletion comparisons (33 vs. 13/23 vs. 11/12/22) More... We found no evidence for association of the 2bp deletion al...... We found no evidence for association of the 2bp deletion alone with any of the three phenotypes More... Negative Flomen, R. H., 2006
TH (TCAT)n TH 1(0/0/1) 1
allele X2 = 6.62, df = 4, P-value =0.157; genoty...... allele X2 = 6.62, df = 4, P-value =0.157; genotype X2 =7.37, df = 9, P-value= 0.599 More... The distribution of alleles and genotypes did not differ si...... The distribution of alleles and genotypes did not differ significantly between controls and schizophrenics More... Negative Burgert, E., 1998
D18S453 1(1/0/0) 1
TDT:for SZ, allele 166bp, chi quare=0.243, P-value = 0.6219...... TDT:for SZ, allele 166bp, chi quare=0.243, P-value = 0.6219;allele 168bp, chi quare=1.231, P-value = 0.2673;allele 170bp, chi quare=0.164, P-value = 0.6858;allele 172bp, chi quare=0, P-value = 1 More... No significant association was observed. No significant association was observed. Negative Mukherjee, O.,2006
NDE1 Chr16:15785033 C/G NDE1 1(0/0/1) 1
SZ: MAF=0.0015, P-value=0.15, OR=0.65 SZ: MAF=0.0015, P-value=0.15, OR=0.65 No significant association was observed. No significant association was observed. Negative Kimura, H., 2014
NDE1 Chr16:15785118 C/T NDE1 1(0/0/1) 1
SZ: MAF=0.00076, P-value=0.039, OR=7.1 SZ: MAF=0.00076, P-value=0.039, OR=7.1 We observed a signifiant association between SCZ and this v...... We observed a signifiant association between SCZ and this variant. More... Positive Kimura, H., 2014
NDE1 Chr16:15785177 C/T NDE1 1(1/0/0) 1
SZ: MAF=0.00013, P-value=0.46 SZ: MAF=0.00013, P-value=0.46 No significant association was observed. No significant association was observed. Negative Kimura, H., 2014
D22S1169 1(1/0/0) 1
P-value = 0.0214 in SZ, P-value = 0.0383 in BD and SZ P-value = 0.0214 in SZ, P-value = 0.0383 in BD and SZ SNP rs4468 and D22S1169 showed significant association with...... SNP rs4468 and D22S1169 showed significant association with SZ. More... Positive Severinsen, J. E., 2006 (b)
MAOA A1609G MAOA 1(0/0/1) 1
no P-value was given no P-value was given No G allele was observed in any of the Japanese subjects. No G allele was observed in any of the Japanese subjects. Negative Sasaki, T., 1998
D22S279 1(1/0/0) 1
CLUMP T1 P-value = 0.0322, CLUMP T4 P-value = 0.0174 for SZ...... CLUMP T1 P-value = 0.0322, CLUMP T4 P-value = 0.0174 for SZ; CLUMP T1 P-value = 0.0705, CLUMP T4 P-value = 0.0268 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.0277 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.4644 for BPD and SZ in the Case-Control Sample From Scotland More... In the Scottish sample only D22S279 showed significant sing...... In the Scottish sample only D22S279 showed significant single marker association with SZ More... Positive Severinsen, J. E., 2006 (a)
D22S922 1(0/0/1) 1
P-value = 0.3501 in SZ, P-value = 0.5552 in BD and SZ P-value = 0.3501 in SZ, P-value = 0.5552 in BD and SZ Negative Severinsen, J. E., 2006 (b)
DAOA 3'UTR SNP12 DAOA 1(1/0/0) 1
allelic P-value = 0.73 in Schizophrenia allelic P-value = 0.73 in Schizophrenia We found no evidence for allelic or genotypic association w...... We found no evidence for allelic or genotypic association with any of the polymorphisms studied for schizophrenia. We observed nominally significant evidence (P=.01-.047) for allelic association with 3 of the polymorphisms for bipolar disorder and significant evidence for whole-gene association (P=.04). More... Negative Williams, N. M., 2006
DAOA M12 DAOA 1(0/0/1) 1
Association analysis:allele P-value = 0.048, OR=1.25, genot...... Association analysis:allele P-value = 0.048, OR=1.25, genotype P-value = 0.142, OR=1.34 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Schumacher, J.,2004
DAOA M23 DAOA 1(1/0/0) 1
Association analysis:allele P-value = 0.033, OR=1.28, genot...... Association analysis:allele P-value = 0.033, OR=1.28, genotype P-value = 0.102, OR=1.42 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Schumacher, J.,2004
DAOA M24 DAOA 1(0/0/1) 1
Association analysis:allele P-value = 0.036, OR=1.27, genot...... Association analysis:allele P-value = 0.036, OR=1.27, genotype P-value = 0.068, OR=1.59 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Schumacher, J.,2004
MAOA LPR MAOA 1(0/0/1) 1
Association analysis:Chi square tests:alleles, X2 Association analysis:Chi square tests:alleles, X2= 0.375, P-value = 0.574 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Syagailo, Y. V.,2001
DAO MDAAO4 DAO 1(0/0/1) 1
Association analysis:allele P-value = 0.026, OR=1.33, genot...... Association analysis:allele P-value = 0.026, OR=1.33, genotype P-value = 0.085, OR=1.4 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Schumacher, J.,2004
DAO MDAAO5 DAO 1(0/0/1) 1
Association analysis:allele P-value = 0.019, OR=1.37, genot...... Association analysis:allele P-value = 0.019, OR=1.37, genotype P-value = 0.041, OR=1.52 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Schumacher, J.,2004
DAO MDAAO6 DAO 1(0/0/1) 1
Association analysis:allele P-value = 0.021, OR=1.31, genot...... Association analysis:allele P-value = 0.021, OR=1.31, genotype P-value = 0.058, OR=1.6 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Schumacher, J.,2004
MED12 exon42 duplication MED12 1(0/0/1) 1
Association analysis:TDT, X2=0.57, 1 df, P-value...... Association analysis:TDT, X2=0.57, 1 df, P-value = 0.45 for Bulgaria sample.The rate of the rare allele in the 125 Bulgarian BP patients vs.of Bulgarian SZ patients(1% vs. 4.2%; X2=4.11, 1 df, P-value = 0.043). More... The rate of the rare allele in the 125 Bulgarian BP patient...... The rate of the rare allele in the 125 Bulgarian BP patients was lower than that of Bulgarian SZ patients. More... Trend Kirov, G.,2003
MMP3 1171 5A/6A MMP3 1(0/0/1) 1
Fisher's exact test:1.SZ patients compared with healthy con...... Fisher's exact test:1.SZ patients compared with healthy controls:6A6A genotype: df=1, X2=12.23, P-value < 0.001;5A5A genotype:df=1, X2=16.56, P-value < 0.001;6A allele: df=1, X2=23.40, P-value < 0.001;5A allele:df=1, X2=23.40, P-value < 0.001. 2.SZ patients compared with BD-I patients:6A6A genotype: df=1, X2=5.75, P-value < 0.05;5A5A genotype:df=1, X2=15.66, P-value < 0.001;6A allele: df=1, X2=16.50, P-value < 0.001;5A allele:df=1, X2=16.50, P-value < 0.001. More... The frequencies of 6A6A genotype and 6A allele distribution...... The frequencies of 6A6A genotype and 6A allele distributions of MMP3 in patients with SZ were significantly decreased when compared with controls. In contrast, in patients with SZ, the distributions of 5A5A genotype and 5A allele of MMP3 gene were significantly increased as compared with healthy controls. When the frequencies of genotypes or alleles in schizophrenic patients and bipolar patients were compared, 6A6A genotype and 6A allele in patients with BD-I were significantly higher than patients with SZ. In contrast, 5A5A genotype and 5A allele distributions of MMP3 gene were significantly frequent in patients with SZ. More... Positive Kucukali, C. I.,2009
MTHFD G1958A MTHFD1 1(1/0/0) 1
P-value < 0.0001, OR (95% CI)=2.667 (1.845-3.854) for GG vs...... P-value < 0.0001, OR (95% CI)=2.667 (1.845-3.854) for GG vs.GA & AA genotypes in total patients with BDI; P-value = 0.0398, OR (95% CI)=1.740 (1.024-2.957) in females patients; P-value < 0.0001, OR (95% CI)=3.964 (2.358-6.663) in males patients More... MTHFD1 1958AA or 1958AG genotypes constitute risk factors f...... MTHFD1 1958AA or 1958AG genotypes constitute risk factors for development of bipolar disorder type I (BDI) or schizophrenia. Gender classification of patients indicated significant association only of MTHFD1 1958A allele with schizophrenia in the male patients. More... Positive Kempisty, B., 2007 (b)
MTR A2756G MTR 1(1/0/0) 1
P-value = 0.0160, OR (95% CI)=1.556 (1.085-2.232) for AA vs...... P-value = 0.0160, OR (95% CI)=1.556 (1.085-2.232) for AA vs AG & GG genotypes in total patients with BDI; P-value = 0.1659, OR (95% CI)=1.450 (0.856-2.455) in females patients; P-value = 0.0404, OR (95% CI)=1.680 (1.021-2.763) in males patients More... the MTR 2756GG or 2756AG genotypes constitute significant r...... the MTR 2756GG or 2756AG genotypes constitute significant risk factors in occurrence of schizophrenia. More... Positive Kempisty, B., 2007 (b)
DISC1 A844G DISC1 1(0/0/1) 1
Association analysis:Chi square tests:alleles, P>0.05 Association analysis:Chi square tests:alleles, P>0.05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Devon, R. S.,2001
DISC1 C1460T DISC1 1(0/0/1) 1
Association analysis:Chi square tests:alleles, P>0.05 Association analysis:Chi square tests:alleles, P>0.05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Devon, R. S.,2001
DISC1 G65049 DISC1 1(0/0/1) 1
Association analysis:Chi square tests:alleles, P>0.05 Association analysis:Chi square tests:alleles, P>0.05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Devon, R. S.,2001
DISC1 T11840C DISC1 1(0/0/1) 1
Association analysis:Chi square tests:alleles, P>0.05 Association analysis:Chi square tests:alleles, P>0.05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Devon, R. S.,2001
DISC1 T2163A DISC1 1(0/0/1) 1
Association analysis:Chi square tests:alleles, P>0.05 Association analysis:Chi square tests:alleles, P>0.05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Devon, R. S.,2001
DRD2 5'flanking -141C Ins/Del DRD2 1(0/0/1) 1
genotypic P-value=0.51, X2=1.35, df=2; allelic P-...... genotypic P-value=0.51, X2=1.35, df=2; allelic P-value=0.48, X2=0.5, df=1 More... the schizophrenic and the control group did not differ sign...... the schizophrenic and the control group did not differ significantly regarding genotype frequencies and allele frequencies. More... Negative Stober, G., 1998
SLC6A2 Gly478Ser SLC6A2 1(0/0/1) 1
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Stober, G.,1996
SLC6A2 Thr99Ile SLC6A2 1(0/0/1) 1
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Stober, G.,1996
SLC6A2 Val245Ile SLC6A2 1(0/0/1) 1
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Stober, G.,1996
SLC6A2 Val449Ile SLC6A2 1(0/0/1) 1
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Stober, G.,1996
SLC6A2 Val69Ile SLC6A2 1(0/0/1) 1
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in SCZ groups. No significant differences were found in SCZ groups. Negative Stober, G.,1996
RTN4 3'UTR CAA insertion RTN4 1(0/0/1) 1
chi-square test:genotype, P-value > 0.05;allele, P-value > ...... chi-square test:genotype, P-value > 0.05;allele, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Gregorio, S. P.,2005
GRN C/T GRN 1(1/0/0) 1
Tagging single nucleotide polymorphisms (SNPs) rs2879096 an...... Tagging single nucleotide polymorphisms (SNPs) rs2879096 and rs4792938, along with rs5848, previously shown to be associated with BD and schizophrenia. More... Positive Galimberti, D., 2014
NOS1 exon13 SNP2 NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon15 IVS15+38C/T NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon16 2607C/T NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon17 2712C/T NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon17 IVS17+15A/G NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon18 SNP3 NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon19 IVS19+13T/G NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon20 137244A/G NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon21 3258C/T NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon27 4063G/A NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon27 4065G/A NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon27 4154G/A NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
DRD5 D4S615 DRD5 1(0/0/1) 1
Association analysis:CLUMP program, chi square=20.5, df=5, ...... Association analysis:CLUMP program, chi square=20.5, df=5, P-value = 0.001 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Muir, W. J.,2001
NOS1 exon27 IVS27+14T/G NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon27 IVS27+9C/A NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon27 SNP5 NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon29 SNP4 NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 exon7 IVS7-15C/G NOS1 1(0/1/0) 1
Mutations and SNPs detected in the mutational analysis Mutations and SNPs detected in the mutational analysis Trend Reif, A., 2006 (a)
NOS1 SNP1 NOS1 1(0/0/1) 1
P-value = 0.154, X2=2.03, df=2 in unsystematic S...... P-value = 0.154, X2=2.03, df=2 in unsystematic SCZ, P-value = 0.004, X2=8.42, df=2 in systematic SCZ, P-value = 0.020, X2=5.42, df=2 in total sample with SCZ More... SNP1 A/A and A/G genotypes were significantly more frequent...... SNP1 A/A and A/G genotypes were significantly more frequent among schizophrenic patients than among controls; there was no significant effect in the group A SCZ subgroup; the association between SNP1 and SCZ was mainly due to considerably higher frequencies of the A/A and A/ G genotypes in the group B SCZ subgroup More... Positive Reif, A., 2006 (a)
FEZ1 IVS3+2509C>T FEZ1 1(0/0/1) 1
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 0.549, genotype P-value = 0.587 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Yamada, K.,2004
FEZ1 IVS4+1077T>C FEZ1 1(0/0/1) 1
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 0.824, genotype P-value = 0.744 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Yamada, K.,2004
NR2E1 g. -1429 NR2E1 1(0/0/1) 1
X2=0.05, OR (95% CI)=1.07 (0.60-1.91), P-value =...... X2=0.05, OR (95% CI)=1.07 (0.60-1.91), P-value = 0.819 for SZ. More... No association was detected with schizophrenia. No association was detected with schizophrenia. Negative Kumar, R. A., 2008
FEZ1 IVS9+66A>T FEZ1 1(0/0/1) 1
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 0.952, genotype P-value = 0.738 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Yamada, K.,2004
NRG1 exon 11 Val>Leu 1(0/0/1) 1
For SZ:0.68/0.40 model:Pearson Chi-Square/P-value = 0.91/0....... For SZ:0.68/0.40 model:Pearson Chi-Square/P-value = 0.91/0.34, Yates Chi-Square/P-value = 0.04/0.84, Pearson Chi-Square/P-value = 0.12/0.72;Dominant model:Fisher exact P-value = 1 More... No significant association was observed. No significant association was observed. Negative Moon, E.,2011
NRG1 SNP8NRG221132 NRG1 1(0/0/1) 1
Individual P-value = 0.994 for SCZ , Individual P-value = 0...... Individual P-value = 0.994 for SCZ , Individual P-value = 0.7566 for SCZ and BP More... Negative Thomson, P. A., 2007
PIK3C3 -432C->T PIK3C3 1(1/0/0) 1
Allele frequency SZ vs. CONT, O2=1.31, P-value =...... Allele frequency SZ vs. CONT, O2=1.31, P-value = 0.25 in American, Allele frequency SZ vs. CONT in Ashkenazi Jews, Fisher statistic=5.67, P-value = 0.02, Allele frequency SZ vs. CONT in Sephardic Jews, Fisher statistic=5.65, P-value = 0.02. Combined Ashkenazi and Sephardic sample SZ vs. CONT, Fisher statistic=12.81, P-value = 0.0003. More... In the U.S. sample, there was no significant difference in ...... In the U.S. sample, there was no significant difference in the allele distribution between control subjects and patients with SZ and BD. A statistically significant difference in allele distribution was also detected in a cohort of patients with SZ from Israel. More... Positive Stopkova, P., 2004 (a)
PIK3C3 promoter -86insC PIK3C3 1(0/1/0) 1
no P-value no P-value PIK3C3 promoter polymorphism detected in this study PIK3C3 promoter polymorphism detected in this study Trend Stopkova, P., 2004 (a)
PIK4CA -31(A>G) PI4KA 1(0/0/1) 1
Association analysis:SZ vs controls, alleles P-value = 0.28...... Association analysis:SZ vs controls, alleles P-value = 0.28, X2=1.19;genotypes, P-value = 0.36, X2=2.02. More... No significant association was observed. No significant association was observed. Negative Saito, T.,2003
PIK4CA E2079Q PI4KA 1(0/0/1) 1
Association analysis:SZ vs controls, alleles P-value = 0.85...... Association analysis:SZ vs controls, alleles P-value = 0.85, X2=0.038; genotypes, P-value = 0.22, X2=2.99. More... No significant association was observed. No significant association was observed. Negative Saito, T.,2003
GNB3 C825T GNB3 1(0/0/1) 1
Association analysis:Schizophrenics v. controls: genotype: ...... Association analysis:Schizophrenics v. controls: genotype: X2=2.3, 2 df, P-value = 0.32; allele: X2=2.3, 1 df, P-value = 0.13 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Kunugi, H.,2002
PIK4CA R2259C PI4KA 1(0/0/1) 1
Association analysis:SZ vs controls, alleles P-value = 0.15...... Association analysis:SZ vs controls, alleles P-value = 0.15, X2=2.12; genotypes (combined 1, 1 vs 1, 2+2, 2, P-value = 0.21, X2=1.60) More... No significant association was observed. No significant association was observed. Negative Saito, T.,2003
PIP5K2A -1007C>T PIP4K2A 1(0/0/1) 1
Pearson X2 test:genotypes:schizophrenia (SZ): TT...... Pearson X2 test:genotypes:schizophrenia (SZ): TT +CT versus CC: X2=1.36, P-value = 0.24, alleles: X2 =2.24, P-value = 0.13, More... No significant association was observed. No significant association was observed. Negative Stopkova, P.,2005
GRIN2B A5806C GRIN2B 1(1/0/0) 1
P-value (corrected)=0.305, X2=2.373, df=2 of all...... P-value (corrected)=0.305, X2=2.373, df=2 of allele frequencies and association analysis in the schizophrenia case-control sample; FBAT P-value = 0.73, z=0.349 in SCZ triads More... No association was found between the A5806C polymorphism an...... No association was found between the A5806C polymorphism and either schizophrenia or bipolar disorder (both families and case-control). More... Negative Martucci, L., 2006
GRIN2B T5988C GRIN2B 1(1/0/0) 1
P-value (corrected)=0.654, X2=0.849, df=2 of all...... P-value (corrected)=0.654, X2=0.849, df=2 of allele frequencies and association analysis in the schizophrenia case-control sample; FBAT P-value = 0.56, z=0.6 in SCZ triads More... The T5988C polymorphism was not associated with schizophren...... The T5988C polymorphism was not associated with schizophrenia in either sample. More... Negative Martucci, L., 2006
PIP5K2A Exon9 Intron 9 CT repeat PIP4K2A 1(1/0/0) 1
Association analysis:all alleles with 29 repeats or less we...... Association analysis:all alleles with 29 repeats or less were compared with alleles greater than 29 repeats, X2=0.02, P-value = 0.83 More... No significant association was observed. No significant association was observed. Negative Stopkova, P.,2003
GRM3 +1131C/T GRM3 1(0/0/1) 1
Association analysis:Fisher's exact test, P-value = 0.0022;...... Association analysis:Fisher's exact test, P-value = 0.0022;TDT, =0.8, P-value = 0.371 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Marti, S. B.,2002
PRODH-1482 PRODH 1(0/0/1) 1
Armitage trend test:P-value(odds ratio)=0.334(1.17) for SZ Armitage trend test:P-value(odds ratio)=0.334(1.17) for SZ No significant associations were found in SZ. No significant associations were found in SZ. Negative Abou Jamra, R.,2005(a)
PRODH-1945 PRODH 1(0/0/1) 1
Armitage trend test:P-value(odds ratio)=0.891(1.02) for SZ Armitage trend test:P-value(odds ratio)=0.891(1.02) for SZ No significant associations were found in SZ. No significant associations were found in SZ. Negative Abou Jamra, R.,2005(a)

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Last update: March 31, 2016