BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	NRG1 SNP8NRG243177
Type	point mutation
Related Gene	NRG1
No. of Study	3 (Positive: 0; Negative 3; Trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Variant related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cassidy, F., 2006	G/A		TDT P-value = 0.82, X²=0.05	From the single marker association analysis, there was no ev..... More From the single marker association analysis, there was no evidence of association of NRG2 with BPAD in this sample. Less	Negative
Thomson, P. A., 2007			Individual P-value = 0.3379 for BP, Individual P-value = 0.5341 for SCZ and BP		Negative
Georgieva, L.,2008	A/G		TDT P-value = 0.25, X²=1.31		Negative

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A., 2007	Individual P-value = 0.8945 for SCZ , Individual P-value = 0.5341 for SCZ and BP		Negative

Overlap with MDD from cross-disorder studies (count: 0)