BDgene

Study Report

Basic Info
Reference
Citation Vogt, I. R., D. Shimron-Abarbanell, et al. (2000). "Investigation of the human serotonin 6 [5-HT6] receptor gene in bipolar affective disorder and schizophrenia." Am J Med Genet 96(2): 217-221.
Disease Type Bipolar Disorder & Schizophrenia
Study Design case-control
Study Type Candidate-gene association study
Sample Size 45 bipolar affective patients, 46 schizophrenic patients,and 46 unrelated controls
SNP/Region/Marker Size 6 variants
Predominant Ethnicity Caucasian
Population German

Detail Info

Genetic factors reported by this study for BD
Other variants reported by this study for BD (count: 4)

Genes reported by this study for BD (count: 1)

Genetic factors reported by this study for SZ and/or MDD
Other variants reported by this study for SZ/MDD
Disease Variant Name Related Gene Type Statistical Values Description Result Category
SZ HTR6 126G/T HTR6 point mutation Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.485, allele P-value = 0.497 No significant association was observed in SZ. Negative
SZ HTR6 873+128A/C HTR6 point mutation Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.119, allele P-value = 0.114 No significant association was observed in SZ. Negative
SZ HTR6 267C/T HTR6 point mutation Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.274, allele P-value = 0.249 No significant association was observed in SZ. Negative

Genes reported by this study for SZ/MDD
Disease Gene Description Result Category
SZ HTR6 In schizophrenia patients no significant difference was observed. Negative