BDgene

Other Variant Report

Basic Info
Name HTR6 267C/T
Type point mutation
Related Gene HTR6
No. of Study 2 (Positive: 1; Negative 1; Trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES

Variant related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Hong, C. J.,1999 C/T Chi square test:genotype P-value = 0.263;allele P-value = 0.093 No significant differences were found in bipolar groups. Negative
Vogt, I. R.,2000 C/T Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.0015, allele P-value = 0.023;TDT=1.59 (P-value = 0.208). Significant association was found in BPD patients. Positive

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Vogt, I. R.,2000 Assocaition analysis:Fisher's exact test, two-tailed, genotype P-value = 0.274, allele P-value = 0.249 No significant association was observed in SZ. Negative

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Hong, C. J.,1999 Chi square test:genotype P-value = 0.372;allele P-value = 0.628 No significant differences were found in major depression groups. Negative