BDgene

Other Variant Report

Basic Info
Name SLC12A6 32418760(G/A)
Type point mutation
Related Gene SLC12A6
No. of Study 1 (Positive: 1; Negative 0; Trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO

Variant related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Meyer, J.,2005 G/A For Bipolar disorder vs. controls:Allele, Exact test, P-value < 0.0001, Odds ratio=9.29 (2.76-31.31);genotype, Exact test, P-value = 0.0000, Odds ratio=(2.87-33.57).For All cases vs.controls:Allele, X2 test, 1 d.f., X2=11.63, P-value = 0.0007, Odds ratio=5.72 (1.85-17.68);genotype, Armitage trend test, Z=-3.44, P-value = 0.0006, Odds ratio=5.90 (1.89-18.37).
Significant associations were found in BPD patients and all ..... More
Positive

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Meyer, J.,2005 For Schizophrenia vs. controls:Allele, Exact test, P-value = 0.0596, Odds ratio=3.54 (0.94-13.31) ;genotype, Exact test, P-value = 0.0586, Odds ratio=3.60 (0.95-13.65) No significant associations were found in SZ. Negative

Overlap with MDD from cross-disorder studies (count: 0)