Gene Report

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Basic Info

Approved Symbol	ERDA1
Approved Name	expanded repeat domain, CAG/CTG 1
Location	17q21.3
Position	chr17:0-0,
External Links	HGNC: 3442 Entrez Gene: 9030
No. of Studies	4 (Positive: 0; Negative: 4; trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Gene related studies (count: 4)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Meira-Lima, I. V.,2001	Other variant: ERDA1_CAG/CTG repeat	Our data do not support the hypothesis that variation at the polymorphic CAG/CTG repeat loci ERDA-1 influence susceptibility to BPAD in our sample.	Negative	Comment on Study
Jin, D. K.,2001	Other variant: ERDA1_microsatellite	ERDA1 may not be a risk factor for BPAD in Korean population.	Negative	Comment on Study
Del-Favero, J.,2002	Other variant: ERDA1_microsatellite	We conclude that the ERDA-1 locus is not related to the BP phenotype.	Negative	Comment on Study
Vincent, J. B.,1999(b)	Other variant: ERDA1_microsatellite	We observed no increase in frequency of larger alleles (>37 repeats) in affected individuals at ERDA1.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 0)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Variant Name	Variant Type	Location in Gene	No. of Studies (Positive/Negative/Trend)
ERDA1_microsatellite	microsatellite		3 (0/3/0)
ERDA1_CAG/CTG repeat	microsatellite		1 (0/1/0)

Gene related regions (count: 21)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 17_1.5cM	chr17:0-0	1 (0/0/1)
Chr 17_10.7cM	chr17:0-0	1 (0/1/0)
Chr 17_100cM	chr17:0-0	1 (0/1/0)
Chr 17_109cM	chr17:0-0	1 (0/0/1)
Chr 17	chr17:0-83257441	3 (0/3/0)
Chr 17_54.6cM	chr17:0-0	1 (0/1/0)
17p13	chr17:0-10800000	3 (0/3/0)
Chr 17_3.9cM	chr17:0-0	1 (0/0/1)
Chr 17_73.6cM	chr17:0-0	1 (0/0/1)
Chr 17_6.97cM	chr17:0-0	1 (0/1/0)
Chr 17_111cM	chr17:0-0	1 (0/0/1)
Chr 17_10cM	chr17:0-0	1 (0/0/1)
Chr 17_15.71cM	chr17:0-0	1 (0/1/0)
Chr 17_126.5cM	chr17:0-0	1 (0/0/1)
Chr 17_98cM	chr17:0-0	1 (0/1/0)
Chr 17_97.6cM	chr17:0-0	1 (0/0/1)
Chr 17_83.6Mb	chr17:0-0	1 (0/0/1)
Chr 17_75cM	chr17:0-0	1 (0/0/1)
Chr 17_9.14cM	chr17:0-0	1 (0/1/0)
Chr 17_88.2Mb	chr17:0-0	1 (0/0/1)
17q_62cM	chr17:0-0	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Reference	Description	Result Category
10395212	We observed no increase in frequency of larger alleles (>37 repeats) in affected individuals at ERDA1.	Negative

Reference	ID in SZGene	Result Category
10395212	119	Negative
10909126	119	Negative

Gene relationship with MDD

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Region: chr17:0..0 View in gBrowse