Gene Report

Basic Info
Approved Symbol RTN4
Symbol Alias NSP-CL, KIAA0886, NOGO, ASY
Approved Name reticulon 4
Location 2p16.1
Position chr2:54972187-55112621, -1
External Links HGNC: 14085
Entrez Gene: 57142
Ensembl: ENSG00000115310
UCSC: uc002rye.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gregorio, S. P.,2005 Other variant: RTN4_3'UTR_CAA insertion After exhaustively crossing clinical and ethnographical data we failed to demonstrate any association of this Nogo polymorphism with SCZ or BPD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 24)

GO terms by PBA (count: 1)

GO terms by database search (count: 23)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 17)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 7)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 7)

Gene relationship with MDD

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Region: chr2:54972187..55112621 View in gBrowse
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