Gene Report

Basic Info
Approved Symbol MMP3
Previous Symbol STMY1, STMY
Approved Name matrix metallopeptidase 3
Previous Name matrix metalloproteinase 3 (stromelysin 1, progelatinase), "stromelysin 1"
Location 11q22.3
Position chr11:102835801-102843803, -1
External Links HGNC: 7173
Entrez Gene: 4314
Ensembl: ENSG00000149968
UCSC: uc001phj.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Kucukali, C. I.,2009 Other variant: MMP3_1171_5A/6A No significant differences were found in the allele or genotype distribution in patients with BD-I compared with controls. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 22)

GO terms by PBA (count: 2)

GO terms by database search (count: 20)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 16)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

View in gBrowse

Region: chr11:102835801..102843803 View in gBrowse
View in gBrowse