Region Report

Basic Info

Region Name	Chr 1
Chromosome Position	chr1:0-248956422
No. of Studies (Positive/Negative/Trend)	2(0/2/0)

Region related studies (count: 2)

Reference	Markers	Statistical Values	Author Comments	Result Category
Murphy, V. E.,2000	D1S255	Linkage analysis: broad model, NPL = -0.193, P-value = 0.58;...... Linkage analysis: broad model, NPL = -0.193, P-value = 0.58; narrow model, NPL = 0.089, P-value = 0.45 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Badner, J. A.,2002		Meta analysis: Location: 238, Single Analysis MSP = 0.01, Be...... Meta analysis: Location: 238, Single Analysis MSP = 0.01, Best Analysis MSP = 0.06 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 89)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
JAK1	Janus kinase 1	1p32.3-p31.3	1(0/1/0)
CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit	1q32	1(0/1/0)
RABGAP1L	RAB GTPase activating protein 1-like	1q24	1(0/1/0)
MYOM3	myomesin 3	1p36	1(0/0/1)
DISC1	disrupted in schizophrenia 1	1q42.1	18(10/7/1)
PLXNA2	plexin A2	1q32.2	1(1/0/0)
CNR2	cannabinoid receptor 2 (macrophage)	1p	1(1/0/0)
DCAF6	DDB1 and CUL4 associated factor 6	1q23.3	1(0/1/0)
GJA5	gap junction protein, alpha 5, 40kDa	1q21.2	1(1/0/0)
GRIK3	glutamate receptor, ionotropic, kainate 3	1p34.3	1(1/0/0)
MIR137	microRNA 137	1p21.3	1(1/0/0)
GCLM	glutamate-cysteine ligase, modifier subunit	1p21	1(0/0/1)
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	1p36.3	16(10/6/0)
FMO5	flavin containing monooxygenase 5	1q21.1	1(1/0/0)
LINC01141	long intergenic non-protein coding RNA 1141	1p36.12	1(0/0/1)
ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	1q23.2	1(1/0/0)
MTR	5-methyltetrahydrofolate-homocysteine methyltransferase	1q43	2(1/1/0)
EDARADD	EDAR-associated death domain	1q42.3	1(1/0/0)
PTBP2	polypyrimidine tract binding protein 2	1p21.3	1(0/0/1)
GJA8	gap junction protein, alpha 8, 50kDa	1q21.1	1(1/0/0)
ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	1p13	1(1/0/0)
PTGFR	prostaglandin F receptor (FP)	1p31.1	1(1/0/0)
DAB1	Dab, reelin signal transducer, homolog 1 (Drosophila)	1p32-p31	1(0/1/0)
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	1q25.3	1(1/0/0)
EXTL1	exostosin-like glycosyltransferase 1	1p36.1	1(1/0/0)
RGS5	regulator of G-protein signaling 5	1q23.1	1(0/0/1)
LRRIQ3	leucine-rich repeats and IQ motif containing 3	1p31.1	1(0/0/1)
CHD1L	chromodomain helicase DNA binding protein 1-like	1q21.1	1(1/0/0)
PPIEL	peptidylprolyl isomerase E-like pseudogene	1p34.2	1(0/0/1)
TNR	tenascin R	1q24	2(0/2/0)
PER3	period circadian clock 3	1p36.23	7(3/4/0)
C1orf110	chromosome 1 open reading frame 110	1q23.3	2(1/0/1)
ANKRD35	ankyrin repeat domain 35	1q21.1	1(1/0/0)
HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	1p36-p35	3(1/2/0)
RGS4	regulator of G-protein signaling 4	1q23.3	6(3/2/1)
IL10	interleukin 10	1q31-q32	1(0/1/0)
NPPB	natriuretic peptide B	1p36.2	1(1/0/0)
KCNN3	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3	1q21.3	7(1/6/0)
RGS7	regulator of G-protein signaling 7	1q43	1(0/1/0)
GSTM1	glutathione S-transferase mu 1	1p13.3	1(1/0/0)
NPHP4	nephronophthisis 4	1p36	1(1/0/0)
NFIA	nuclear factor I/A	1p31.3-p31.2	1(0/1/0)
RLF	rearranged L-myc fusion	1p32	1(0/1/0)
CFAP57	cilia and flagella associated protein 57	1p34.2	1(0/1/0)
TAS1R3	taste receptor, type 1, member 3	1p36	1(0/0/1)
ARV1	ARV1 homolog (S. cerevisiae)	1q42.2	1(0/0/1)
OLFM3	olfactomedin 3	1p22	1(1/0/0)
PRKCZ	protein kinase C, zeta	1p36.33-p36.2	1(1/0/0)
TSNAX	translin-associated factor X	1q42.2	4(3/1/0)
IFI44L	interferon-induced protein 44-like	1p22.3	1(0/1/0)
DNAH14	dynein, axonemal, heavy chain 14	1q42.13	1(0/0/1)
MPC2	mitochondrial pyruvate carrier 2	1q24	1(0/1/0)
ATAD3C	ATPase family, AAA domain containing 3C	1p36.33	1(0/0/1)
NEK7	NIMA-related kinase 7	1q31.3	2(0/1/1)
DNAJC16	DnaJ (Hsp40) homolog, subfamily C, member 16	1p36.1	1(0/1/0)
MIR2682	microRNA 2682	1	1(1/0/0)
WDR65	cilia and flagella associated protein 57	1p34.2	0
STX12	syntaxin 12	1p35.3	1(0/1/0)
CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	1q21.3	1(1/0/0)
ZNF678	zinc finger protein 678	1q42.13	1(0/1/0)
ROR1	receptor tyrosine kinase-like orphan receptor 1	1p31.3	1(0/0/1)
ALDH9A1	aldehyde dehydrogenase 9 family, member A1	1q24.1	1(0/1/0)
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	1q42.2	1(1/0/0)
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	1p36.1	1(0/1/0)
HCRTR1	hypocretin (orexin) receptor 1	1p33	1(1/0/0)
FBXO28	F-box protein 28	1q42.12	1(0/1/0)
TMEM222	transmembrane protein 222	1p36.11	1(0/0/1)
NUF2	NUF2, NDC80 kinetochore complex component	1q23.3	1(1/0/0)
NME7	NME/NM23 family member 7	1q24.2	1(0/1/0)
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	1p36.3-p34.3	1(0/1/0)
RYR2	ryanodine receptor 2 (cardiac)	1q43	1(1/0/0)
CHRM3	cholinergic receptor, muscarinic 3	1q43	1(0/1/0)
FAM20B	family with sequence similarity 20, member B	1q25.2	1(0/1/0)
NGF	nerve growth factor (beta polypeptide)	1p13.1	2(1/1/0)
BCL9	B-cell CLL/lymphoma 9	1q21	1(1/0/0)
ASTN1	astrotactin 1	1q25.2	1(1/0/0)
IRF2BP2	interferon regulatory factor 2 binding protein 2	1q42.3	1(0/1/0)
FABP3	fatty acid binding protein 3, muscle and heart	1p33-p32	2(1/1/0)
AVPR1B	arginine vasopressin receptor 1B	1q32	4(3/1/0)
VAMP3	vesicle-associated membrane protein 3	1p36.23	1(0/1/0)
LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	1p32.3	1(1/0/0)
FAAH	fatty acid amide hydrolase	1p35-p34	2(0/2/0)
RC3H1	ring finger and CCCH-type domains 1	1q25.1	1(0/1/0)
ACP6	acid phosphatase 6, lysophosphatidic	1q21	1(1/0/0)
LEPR	leptin receptor	1p31	1(1/0/0)
PDE4B	phosphodiesterase 4B, cAMP-specific	1p31	3(1/2/0)
KLHL20	kelch-like family member 20	1q25.1	1(0/1/0)
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	1p36	1(0/0/1)
PLD5	phospholipase D family, member 5	1q43	1(0/1/0)

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Region: chr1:0..248956422 View in gBrowse