Gene Report

Basic Info
Approved Symbol IL10
Symbol Alias CSIF, TGIF, IL10A, IL-10
Approved Name interleukin 10
Name Alias cytokine synthesis inhibitory factor, "T-cell growth inhibitory factor"
Location 1q31-q32
Position chr1:206767602-206772494, -1
External Links HGNC: 5962
Entrez Gene: 3586
Ensembl: ENSG00000136634
UCSC: uc001hen.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Clerici, M.,2009 Other variant: IL10_1082G/A The distribution of cytokines interleukin (IL)-10 polymorphism was not significantly different in the groups. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 53)

GO terms by PBA (count: 2)

GO terms by database search (count: 51)

Gene related KEGG pathways (count: 7)

Gene related BioCarta pathways (count: 5)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 7)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 4)

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Region: chr1:206767602..206772494 View in gBrowse
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