Gene Report

Basic Info
Approved Symbol RGS5
Approved Name regulator of G-protein signaling 5
Previous Name regulator of G-protein signalling 5
Location 1q23.1
Position chr1:163111121-163321791, -1
External Links HGNC: 10001
Entrez Gene: 8490
Ensembl: ENSG00000143248
UCSC: uc001gcn.3
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Smith, E. N.,2009 SNP: rs4657247 SNPs with the strongest statistical evidence for genetic background effects included rs11208285 in ROR1 at 1p31.3 (P=1.4E-06), rs4657247 in RGS5 at 1q23.3 (P=4.1E-06), and rs7078071 in BTBD16 at 10q26.13 (P=4.5E-06). Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 7)

GO terms by PBA (count: 1)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:163111121..163321791 View in gBrowse
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