Gene Report

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Basic Info

Approved Symbol	FBXO28
Symbol Alias	FLJ10766, KIAA0483, Fbx28, CENP-30
Approved Name	F-box protein 28
Name Alias	centromere protein 30
Location	1q42.12
Position	chr1:224114087-224162047, 1
External Links	HGNC: 29046 Entrez Gene: 23219 Ensembl: ENSG00000143756 UCSC: uc001hoh.3
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs1401319	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005515	protein binding	molecular function	IPI[21516116]	563

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Gene	Interactor	Interactor in BDgene?	Experiment Type	PMID
FBXO28	TRAF2	NO	yeast 2-hybrid	16189514

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs1401319	chr1:224146408 - 224146408(1)	intron_variant; NMD_transcript_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
1q42	chr1:223900000-236400000	1 (0/1/0)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr1:224114087..224162047 View in gBrowse