Gene Report

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Basic Info

Approved Symbol	C1orf110
Symbol Alias	MGC48998
Approved Name	chromosome 1 open reading frame 110
Location	1q23.3
Position	chr1:162824458-162868815, -1
External Links	HGNC: 28736 Entrez Gene: 339512 Ensembl: ENSG00000185860 UCSC: uc001gck.2
No. of Studies	2 (Positive: 1; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 2)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Jamain, S., 2014	SNP: rs12031354	It showed nominal evidence for association with BD.	Trend	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0040. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 0)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs12031354	chr1:162892557 - 162892557(1)		1(0/0/1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
1q23	chr1:156600000-165500000	1 (0/1/0)
1p32.1-q31.1	chr1:58500000-190800000	1 (0/1/0)
1q23.3	chr1:160500000-165500000	1 (0/0/1)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:162824458..162868815 View in gBrowse