Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	MYOM3
Symbol Alias	FLJ35961
Approved Name	myomesin 3
Previous Name	myomesin family, member 3
Location	1p36
Position	chr1:24056035-24112175, -1
External Links	HGNC: 26679 Entrez Gene: 127294 Ensembl: ENSG00000142661 UCSC: uc001bin.4
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Goes, F. S.,2012	SNP: rs3934861	OR = 0.8,P-value(Meta) = 0.00000376 Suggestive association was found.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 2)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0031430	M band	cellular component	ISS	2
GO:0042803	protein homodimerization activity	molecular function	ISS	71

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 9)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs3934861	chr1:24105466 - 24105466(1)	intron_variant; non_coding_transcript_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs6686007	chr1:24116417 - 24116417(1)	downstream_gene_variant; upstream_gene_variant
rs11249175	chr1:24113553 - 24113553(1)	upstream_gene_variant
rs12408946	chr1:24110223 - 24110223(1)	intron_variant; upstream_gene_variant
rs6424154	chr1:24101400 - 24101400(1)	intron_variant; non_coding_transcript_variant
rs11249170	chr1:24108105 - 24108105(1)	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant
rs4649185	chr1:24098686 - 24098686(1)	intron_variant; non_coding_transcript_variant
rs7545471	chr1:24099240 - 24099240(1)	intron_variant; non_coding_transcript_variant
rs3885698	chr1:24097751 - 24097751(1)	intron_variant; non_coding_transcript_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
1p35-p36	chr1:0-34300000	1 (1/0/0)
1p33-p36	chr1:0-50200000	1 (0/0/1)
1p36	chr1:0-27600000	1 (0/1/0)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr1:24056035..24112175 View in gBrowse