Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	EDARADD
Approved Name	EDAR-associated death domain
Location	1q42.3
Position	chr1:236348257-236484914, 1
External Links	HGNC: 14341 Entrez Gene: 128178 Ensembl: ENSG00000186197 UCSC: uc001hxu.1
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0032. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0030154	cell differentiation	biological process	IEA	31

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005737	cytoplasm	cellular component	IEA	322
GO:0042475	odontogenesis of dentin-containing tooth	biological process	IEA	8
GO:0005515	protein binding	molecular function	IPI[25416956]	563
GO:0061153	trachea gland development	biological process	IEA	1
GO:0001942	hair follicle development	biological process	IEA	4
GO:0007165	signal transduction	biological process	IEA	136

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:236348257..236484914 View in gBrowse