Gene Report

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Basic Info

Approved Symbol	DNAH14
Previous Symbol	C1orf67
Symbol Alias	Dnahc14, HL-18, HL18, DKFZp781B1548, MGC27277
Approved Name	dynein, axonemal, heavy chain 14
Previous Name	dynein, axonemal, heavy polypeptide 14, "chromosome 1 open reading frame 67"
Location	1q42.13
Position	chr1:224896262-225399292, 1
External Links	HGNC: 2945 Entrez Gene: 127602 Ensembl: ENSG00000185842 UCSC: uc001how.2
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Cruceanu, C., 2013	Other variant: DNAH14_Chr1:225586971_A/T	Rare variant was found within this gene.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0007018	microtubule-based movement	biological process	IEA	7
GO:0003777	microtubule motor activity	molecular function	IEA	8
GO:0005524	ATP binding	molecular function	IEA	118
GO:0005874	microtubule	cellular component	IEA	24
GO:0008152	metabolic process	biological process	IEA	50
GO:0005737	cytoplasm	cellular component	IEA	322
GO:0005929	cilium	cellular component	IEA	10
GO:0030286	dynein complex	cellular component	IEA	1

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Variant Name	Variant Type	Location in Gene	No. of Studies (Positive/Negative/Trend)
DNAH14_Chr1:225586971_A/T	Stoploss	Chr1:225586971	1 (0/0/1)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
1q42	chr1:223900000-236400000	1 (0/1/0)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr1:224896262..225399292 View in gBrowse