Gene Report

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Basic Info

Approved Symbol	CFAP57
Previous Symbol	WDR65
Symbol Alias	FLJ32000
Approved Name	cilia and flagella associated protein 57
Previous Name	WD repeat domain 65
Location	1p34.2
Position	chr1:43172149-43254358, 1
External Links	HGNC: 26485 Entrez Gene: 149465 Ensembl: ENSG00000243710 UCSC: uc021omk.1
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs11210815, rs3820588, rs639476, rs663824	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 0)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 4)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs639476	chr1:43165731 - 43165731(1)	intron_variant; non_coding_transcript_variant	1(0/1/0)
rs11210815	chr1:43222406 - 43222406(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1(0/1/0)
rs663824	chr1:43183837 - 43183837(1)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	1(0/1/0)
rs3820588	chr1:43234142 - 43234142(1)	intron_variant; non_coding_transcript_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
1p34.2	chr1:39600000-43700000	1 (0/0/1)
1p33-p36	chr1:0-50200000	1 (0/0/1)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:43172149..43254358 View in gBrowse