Gene Report

Basic Info
Approved Symbol FAAH
Symbol Alias FAAH-1
Approved Name fatty acid amide hydrolase
Location 1p35-p34
Position chr1:46394265-46413848, 1
External Links HGNC: 3553
Entrez Gene: 2166
Ensembl: ENSG00000117480
UCSC: uc001cpu.2
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Pisanu, C., 2013 SNP: rs17361936, rs6429600, rs4141964, rs324420, rs324419, rs11576941 As a whole, our results do not support a clear role of FAAH in BD and lithium response. Negative Comment on Study
Monteleone, P.,2010 SNP: rs324420 A case-control study using the missense polymorphism, 2316A>G (Ile772Met), and the tetranucleotide repeat (TTTA)n showed no significant association with mood disorders in Japanese samples. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 10)

GO terms by PBA (count: 1)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 16)

Literature-origin SNPs (count: 6)

LD-proxies (count: 10)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr1:46394265..46413848 View in gBrowse
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