Gene Report

Basic Info
Approved Symbol HTR1D
Previous Symbol HTRL
Symbol Alias RDC4, HT1DA, 5-HT1D
Approved Name 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
Previous Name 5-hydroxytryptamine (serotonin) receptor 1D
Location 1p36.3-p34.3
Position chr1:23191895-23194729, -1
External Links HGNC: 5289
Entrez Gene: 3352
Ensembl: ENSG00000179546
UCSC: uc001bgn.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Vincent, J. B.,1999(a) Other variant: HTR1D_TaqI Polymorphism, HTR1D_HincII Polymorphism No significant differences were found in bipolar groups. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 3)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr1:23191895..23194729 View in gBrowse
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