Gene Report

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Basic Info

Approved Symbol	ARV1
Approved Name	ARV1 homolog (S. cerevisiae)
Previous Name	ARV1 homolog (yeast)
Location	1q42.2
Position	chr1:230978981-231000595, 1
External Links	HGNC: 29561 Entrez Gene: 64801 Ensembl: ENSG00000173409 UCSC: uc001huh.3
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Cruceanu, C., 2013	Other variant: ARV1_Chr1:231114915_A/T	Rare variant was found within this gene.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005789	endoplasmic reticulum membrane	cellular component	TAS	52
GO:0090181	regulation of cholesterol metabolic process	biological process	IEA	2
GO:0006665	sphingolipid metabolic process	biological process	IEA	6
GO:0008206	bile acid metabolic process	biological process	IEA	2
GO:0030301	cholesterol transport	biological process	IEA	3
GO:0055085	transmembrane transport	biological process	TAS	77

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Variant Name	Variant Type	Location in Gene	No. of Studies (Positive/Negative/Trend)
ARV1_Chr1:231114915_A/T	Missense	Chr1:231114915	1 (0/0/1)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
1q42	chr1:223900000-236400000	1 (0/1/0)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr1:230978981..231000595 View in gBrowse