Gene Report

Basic Info
Approved Symbol PLXNA2
Previous Symbol PLXN2
Symbol Alias OCT, FLJ11751, FLJ30634, KIAA0463
Approved Name plexin A2
Name Alias plexin 2, "plexin-A2", "semaphorin receptor OCT", "transmembrane protein OCT"
Location 1q32.2
Position chr1:208022242-208244320, -1
External Links HGNC: 9100
Entrez Gene: 5362
Ensembl: ENSG00000076356
UCSC: uc001hgz.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Hattori, E.,2009 SNP: rs6540451 After the two-stage analysis, markers in this gene remained nominally significant (allelic P<0.05) with the same allele being consistently over-represented in both the first and the follow-up stages. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 15)

GO terms by PBA (count: 3)

GO terms by database search (count: 12)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 6)

Related other genetic factors
Gene related SNPs (count: 11)

Literature-origin SNPs (count: 1)

LD-proxies (count: 10)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 5)

Gene relationship with MDD

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Region: chr1:208022242..208244320 View in gBrowse
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