Gene Report

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Basic Info

Approved Symbol	PLD5
Symbol Alias	FLJ40773
Approved Name	phospholipase D family, member 5
Location	1q43
Position	chr1:242082986-242524696, -1
External Links	HGNC: 26879 Entrez Gene: 200150 Ensembl: ENSG00000180287 UCSC: uc001hzn.2
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Djurovic, S.,2010	SNP: rs6679053	No significant association of this gene was observed in BD.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 3)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0003824	catalytic activity	molecular function	IEA	5
GO:0008152	metabolic process	biological process	IEA	50

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs1553441	chr1:242546741 - 242546741(1)		1(0/1/0)
rs6679053	chr1:242122402 - 242122402(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 1	chr1:0-248956422	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr1:242082986..242524696 View in gBrowse