Markers |
Haplotype |
Related Gene(s)/Region(s) |
Overlap with MDD |
Statistical Results |
Description |
Result Category |
Reference |
|
rs11178997 - rs10748185 - rs2129575 - rs1843809 |
A-G-T-T |
TPH2
|
global P-value = 0.......
global P-value = 0.04, P-value = 0.002
More...
|
We identified a sig......
We identified a significant difference in haplotype distribution between patients with UP disorder and control individuals for hapblock 2 (Pglobal=.04), which is the result of a specific decrease in the frequency of haplotype AGTT, from 5% in control individuals to 0.4% in patients with UP disorder.
More...
|
Positive
|
Van Den Bogaert, A., 2006 (a) |
|
rs7452939 - rs6903874 - rs6937506 |
|
TAAR6
|
Global X<sup>......
Global X<sup>2</sup>=8.80, df=3, P-value = 0.031
More...
|
There were signific......
There were significant global differences in haplotype frequency between BID patients compared to controls.
More...
|
Positive
|
Pae, C. U., 2008 |
|
WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 |
C-T-A |
WFS1
|
Haplotypic associat......
Haplotypic association:Individual P-value = 0.01, OR (95% CI)=1.587(1.116-2.255)
More...
|
Significant associa......
Significant association was found in individual P-value.
More...
|
Positive
|
Koido, K.,2005 |
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
c-a-t |
NOS3
|
P-value = 0.001, pe......
P-value = 0.001, permutation-based P-value = 0.484, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Positive
|
Reif, A., 2006 (b) |
|
rs7546310 - rs821597 |
AT |
DISC1
|
Individual P-value ......
Individual P-value = 0.003, global P-value = 0.034
More...
|
showed an associati......
showed an association with MDD. Individual haplotype analyses showed that this A-T haplotype was over-represented in MDD.
More...
|
Positive
|
Schosser, A., 2010 |
|
rs766288 - rs2492367 - rs6675281 |
ACC |
DISC1
|
|
rs988748 - BDNF_(GT)n - rs6265 |
C-166bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.162; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.765
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs17721321 - rs6085086 - rs3746684 - rs3746682 - rs4815787 |
|
PROKR2
|
likelihood ratio te......
likelihood ratio test:in total samples:Global P-value = 0.000685 in MDD, in male:Global P-value = 0.441 in MDD, in female:Global P-value = 0.0224, Corrected P-value = 0.0448 in MDD.
More...
|
We detected signifi......
We detected significant associations in MDD.
More...
|
Positive
|
Kishi, T.,2009(c) |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-168bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.071; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.188
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs4305745 - rs562047 - rs452939 |
|
TAAR6, HPS70
|
Epistasis between T......
Epistasis between TAAr6 and HSP-70 variations distinguishes MDD patients from controls. CV consistency=9/10; P<0.0010; testing balancing accuracy=0.62.
More...
|
Heterozygosis or ho......
Heterozygosis or homozygosis for the T allele at rs4305745 turned out to be at risk of depressive disorder in the co-occurrence of the C allele at rs562047 and heterozygosis at rs452939.
More...
|
Positive
|
Pae, C. U.,2010 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-170bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.929; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.165
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-172bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.324; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.389
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
C-174bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.001; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.388
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-170bp-A |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.01; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.05
More...
|
Significant associa......
Significant association was found in both global P-value and individual P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-174bp-A |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.085; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.987
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-174bp-G |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.909; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.82
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs988748 - BDNF_(GT)n - rs6265 |
G-176bp-A |
BDNF
|
Haplotypic associat......
Haplotypic association:in Bonn sample, for MDD, global P-value = 0.000054, Bonferroni-Corrected P-value = 0.00065, individual P-value = 0.989; in Munich Sample, for MDD, global P-value = 0.0092, Bonferroni-Corrected P-value = 0.110, individual P-value = 0.081
More...
|
Significant associa......
Significant association was found in global P-value.
More...
|
Positive
|
Schumacher, J.,2005 |
|
rs2284031 - rs909486 - rs738149 |
C-T-G |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for MDD, P-value(odds ratio)=0.0004(0.8)
More...
|
Significant associa......
Significant association was observed in MDD.
More...
|
Positive
|
Chen, P.,2011 |
|
rs2284031 - rs909486 - rs738149 |
T-C-A |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for MDD, P-value(odds ratio)=0.001(1.44)
More...
|
Significant associa......
Significant association was observed in MDD.
More...
|
Positive
|
Chen, P.,2011 |
|
rs7090018 - rs11199993 |
T-G |
FGFR2
|
P-value=0.041, Perm......
P-value=0.041, Permutated P-value=0.347
More...
|
No significant asso......
No significant association was found after permutation.
More...
|
Positive
|
Wang, T.,2012 |
|
rs7090018 - rs11199993 |
T-C |
FGFR2
|
P-value=0.016, Perm......
P-value=0.016, Permutated P-value=0.154
More...
|
No significant asso......
No significant association was found after permutation.
More...
|
Positive
|
Wang, T.,2012 |
|
rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 |
C-C-A-C-T-A-T |
FKBP5
|
P-value=0.043
P-value=0.043
|
haplotypes CCACTAT ......
haplotypes CCACTAT was significantly more frequent in the patients with major depressive disorder as compared to the healthy subjects (p=0.043).
More...
|
Positive
|
Szczepankiewicz A., 2014 |
|
rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 |
A-C-A-T-T-G-T |
FKBP5
|
P-value=0.014
P-value=0.014
|
haplotypes ACATTGT ......
haplotypes ACATTGT was significantly more frequent in the patients with major depressive disorder as compared to the healthy subjects (p=0.014).
More...
|
Positive
|
Szczepankiewicz A., 2014 |
|
(BZRP_exon_Ala147Thr) - ( BZRP_exon_His162Arg) |
|
TSPO
|
Haplotypic associat......
Haplotypic association:P-value = 0.189
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Kurumaji, A.,2001 |
|
(ADCY9_2316A>G) - ( ADCY9_(TTTA)n) |
|
ADCY9
|
Haplotype analysis:......
Haplotype analysis:X<sup>2</sup> test, P-value = 0.375
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Toyota, T.,2002 |
|
rs11178997 - rs10748185 - rs2129575 - rs1843809 |
T-A-G-T |
TPH2
|
global P-value = 0.......
global P-value = 0.04, P-value = 0.67
More...
|
We identified a sig......
We identified a significant difference in haplotype distribution between patients with UP disorder and control individuals for hapblock 2 (Pglobal=.04), which is the result of a specific decrease in the frequency of haplotype AGTT, from 5% in control individuals to 0.4% in patients with UP disorder.
More...
|
Negative
|
Van Den Bogaert, A., 2006 (a) |
|
rs11178997 - rs10748185 - rs2129575 - rs1843809 |
T-G-T-T |
TPH2
|
global P-value = 0.......
global P-value = 0.04, P-value = 0.94
More...
|
We identified a sig......
We identified a significant difference in haplotype distribution between patients with UP disorder and control individuals for hapblock 2 (Pglobal=.04), which is the result of a specific decrease in the frequency of haplotype AGTT, from 5% in control individuals to 0.4% in patients with UP disorder.
More...
|
Negative
|
Van Den Bogaert, A., 2006 (a) |
|
rs11178997 - rs10748185 - rs2129575 - rs1843809 |
T-G-G-T |
TPH2
|
global P-value = 0.......
global P-value = 0.04, P-value = 0.60
More...
|
We identified a sig......
We identified a significant difference in haplotype distribution between patients with UP disorder and control individuals for hapblock 2 (Pglobal=.04), which is the result of a specific decrease in the frequency of haplotype AGTT, from 5% in control individuals to 0.4% in patients with UP disorder.
More...
|
Negative
|
Van Den Bogaert, A., 2006 (a) |
|
rs11178997 - rs10748185 - rs2129575 - rs1843809 |
T-G-G-G |
TPH2
|
global P-value = 0.......
global P-value = 0.04, P-value = 0.67
More...
|
We identified a sig......
We identified a significant difference in haplotype distribution between patients with UP disorder and control individuals for hapblock 2 (Pglobal=.04), which is the result of a specific decrease in the frequency of haplotype AGTT, from 5% in control individuals to 0.4% in patients with UP disorder.
More...
|
Negative
|
Van Den Bogaert, A., 2006 (a) |
|
rs1487275 - rs4474484 |
A-G, C-A, A-A |
TPH2
|
|
rs4131348' target=_blank>rs4131348 - rs4131348' target=_blank>rs4131348 |
C-T |
TPH2
|
|
(GPR50_502-505) - rs13440581 |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for MDD, P-value = 0.1(all), 0.67(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative
|
Thomson, P. A.,2005(b) |
|
rs2072621 - (GPR50_502-505) |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for MDD, P-value = 0.055(all), 0.36(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative
|
Thomson, P. A.,2005(b) |
|
rs2072621 - (GPR50_502-505) - rs13440581 |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for MDD, P-value = 0.14(all), 0.6(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative
|
Thomson, P. A.,2005(b) |
|
rs2072621 - rs13440581 |
|
GPR50
|
Haplotypic associat......
Haplotypic association:, for MDD, P-value = 0.069(all), 0.27(female)
More...
|
No association was ......
No association was observed.
More...
|
Negative
|
Thomson, P. A.,2005(b) |
|
WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 |
C-T-G |
WFS1
|
Haplotypic associat......
Haplotypic association:Individual P-value = 0.06, OR (95% CI)=2.024(0.970-4.223)
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Koido, K.,2005 |
|
WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 |
G-C-A |
WFS1
|
Haplotypic associat......
Haplotypic association:Individual P-value = 0.075, OR (95% CI)=2.107(0.935-4.811)
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Koido, K.,2005 |
|
WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 |
G-C-G |
WFS1
|
Haplotypic associat......
Haplotypic association:Individual P-value = 0.53, OR (95% CI)=1.216(0.666-2.223)
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Koido, K.,2005 |
|
WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 |
G-T-G |
WFS1
|
Haplotypic associat......
Haplotypic association:Individual P-value = 0.072, OR (95% CI)=2.015(0.937-4.386)
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Koido, K.,2005 |
|
rs3738398 - DISC1_-215(TG)8-13 |
[G-(TG)<sub>8</sub>], [G-(TG)<sub>9</sub>], [C-(TG)<sub>12</sub>] |
DISC1
|
global P-value = 1.......
global P-value = 1.00 for unipolar disorder
More...
|
No significant diff......
No significant differences were found in the frequency of these three major haplotypes between mood disorders and control patients
More...
|
Negative
|
Arai, M., 2007 |
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
|
PAWR
|
|
rs960914 - rs2241802 - rs2323019 - rs352203 |
|
FZD3
|
Haplotypic associat......
Haplotypic association:global P-values>0.2
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Hashimoto, R.,2005(b) |
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
GAGTA |
PAWR
|
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
GAACG |
PAWR
|
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
ATGCA |
PAWR
|
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
GAGCG |
PAWR
|
|
rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 |
AAGCA |
PAWR
|
|
rs11939815 - rs11931061 - rs11133385 - rs3736544 - rs1801260 - rs3749474 |
|
CLOCK
|
likelihood ratio te......
likelihood ratio test:haplotype(G-A-A-G-T-T):1.total samples:Global P-value = 0.883 in MDD 2. male samples:Global P-value = 0.461 in MDD 3. female samples:Global P-value = 0.458 in MDD
More...
|
No significant ass......
No significant association was found with MDD.
More...
|
Negative
|
Kishi, T.,2009(a) |
|
rs1000731 - rs7546310 |
AC |
DISC1
|
|
rs1000731 - rs7546310 - rs821597 |
ACC |
DISC1
|
|
rs12133766 - rs1000731 |
GA |
DISC1
|
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
c-a-g |
NOS3
|
P-value = 0.133, pe......
P-value = 0.133, permutation-based P-value = 0.949, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Negative
|
Reif, A., 2006 (b) |
|
rs12133766 - rs1000731 - rs7546310 |
GAC |
DISC1
|
|
rs2492367 - rs6675281 |
TC |
DISC1
|
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
c-b-g |
NOS3
|
P-value = 0.073, pe......
P-value = 0.073, permutation-based P-value = 0.182, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Negative
|
Reif, A., 2006 (b) |
|
rs2492367 - rs6675281 - rs12133766 |
TCG |
DISC1
|
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
c-b-t |
NOS3
|
P-value = 0.249, pe......
P-value = 0.249, permutation-based P-value = 0.696, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Negative
|
Reif, A., 2006 (b) |
|
rs6675281 - rs12133766 - rs1000731 |
CGA |
DISC1
|
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
c-c-t |
NOS3
|
P-value = 0, permut......
P-value = 0, permutation-based P-value = 0.291, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Negative
|
Reif, A., 2006 (b) |
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
t-a-g |
NOS3
|
P-value = 0, permut......
P-value = 0, permutation-based P-value = 0.148, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Negative
|
Reif, A., 2006 (b) |
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
t-b-g |
NOS3
|
P-value = 0.438, pe......
P-value = 0.438, permutation-based P-value = 0.523, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Negative
|
Reif, A., 2006 (b) |
|
rs766288 - rs2492367 |
AC |
TSNAX
DISC1
|
|
NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T |
t-b-t |
NOS3
|
P-value = 0.106, pe......
P-value = 0.106, permutation-based P-value = 0.673, global P-value = 0.542
More...
|
no global haplotype......
no global haplotype association was observed for MD
More...
|
Negative
|
Reif, A., 2006 (b) |
|
rs6313 - rs2070040 - rs1928040 - rs7997012 |
|
HTR2A
|
likelihood ratio te......
likelihood ratio test:Global P-value = 0.198 in MDD, Global P-value = 0.0810 in mood disorders group
More...
|
No significant asso......
No significant association was found with MDD.
More...
|
Negative
|
Kishi, T.,2009(b) |
|
rs1316780 - rs10865660 - rs3796224 - rs1374913 |
|
PROK2
|
likelihood ratio te......
likelihood ratio test:Global P-value = 0.838 in MDD
More...
|
No significant asso......
No significant association was found with MDD.
More...
|
Negative
|
Kishi, T.,2009(c) |
|
rs1630250 - rs766288 - rs6662926 |
C-C-G |
TSNAX
|
Haplotype analysis:......
Haplotype analysis:global P-value = 0.413, individual P-value = 0.28
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Okuda, A.,2010 |
|
rs1630250 - rs766288 - rs6662926 |
C-T-G |
TSNAX
|
Haplotype analysis:......
Haplotype analysis:global P-value = 0.413, individual P-value = 0.258
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Okuda, A.,2010 |
|
rs1630250 - rs766288 - rs6662926 |
G-C-C |
TSNAX
|
Haplotype analysis:......
Haplotype analysis:global P-value = 0.413, individual P-value = 0.0481
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Okuda, A.,2010 |
|
rs1805054 - rs4912138 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.947
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs1805054 - rs4912138 - rs3790757 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.571
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs1805054 - rs4912138 - rs3790757 - rs9659997 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.799
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs3790757 - rs9659997 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.641
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs4912138 - rs3790757 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.435
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs4912138 - rs3790757 - rs9659997 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.647
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs6693503 - rs1805054 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.888
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs6693503 - rs1805054 - rs4912138 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.221
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs6693503 - rs1805054 - rs4912138 - rs3790757 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.256
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs6693503 - rs1805054 - rs4912138 - rs3790757 - rs9659997 |
|
HTR6
|
Haplotype-wise anal......
Haplotype-wise analysis:global P-value = 0.6
More...
|
No significant ass......
No significant association was found .
More...
|
Negative
|
Fukuo, Y.,2010 |
|
rs1170099 - rs9566940 |
A-C |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs1170099 - rs9566940 |
A-T |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs1170099 - rs9566940 |
G-T |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
A-A-C-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
A-A-T-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
T-A-T-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
T-A-T-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs716934 - rs9566931 - rs9315897 - rs2122246 |
T-G-T-G |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs9315885 - rs9532988 - rs1012053 |
C-A-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs9315885 - rs9532988 - rs1012053 |
C-A-C |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs9315885 - rs9532988 - rs1012053 |
T-A-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs9315885 - rs9532988 - rs1012053 |
T-G-A |
DGKH
|
Haplotypic associat......
Haplotypic association:P-value > 0.05 for MDD
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Zeng, Z.,2011 |
|
rs11759115 - rs7769372 |
C-C |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for MDD, global P-value = 0.9977, individual P-value = 0.9239
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Li, J.,2011(a) |
|
rs11759115 - rs7769372 |
T-C |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for MDD, global P-value = 0.9977, individual P-value = 0.9999
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Li, J.,2011(a) |
|
rs11759115 - rs7769372 |
T-T |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for MDD, global P-value = 0.9977, individual P-value = 0.9881
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Li, J.,2011(a) |
|
rs1883901 - rs10807187 - rs9462343 |
A-G-G |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for MDD, global P-value = 0.8458, individual P-value = 0.5224
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Li, J.,2011(a) |
|
rs1883901 - rs10807187 - rs9462343 |
G-G-A |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for MDD, global P-value = 0.8458, individual P-value = 0.9725
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Li, J.,2011(a) |
|
rs1883901 - rs10807187 - rs9462343 |
G-G-G |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for MDD, global P-value = 0.8458, individual P-value = 0.7182
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Li, J.,2011(a) |
|
rs1883901 - rs10807187 - rs9462343 |
G-T-G |
MDGA1
|
Haplotype analysis:......
Haplotype analysis:for MDD, global P-value = 0.8458, individual P-value = 0.9922
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Li, J.,2011(a) |
|
rs2284031 - rs909486 - rs738149 |
C-T-A |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for MDD, P-value(odds ratio)=0.225(1.16)
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Chen, P.,2011 |
|
rs2284031 - rs909486 - rs738149 |
T-C-G |
CSF2RB
|
Haplotype analysis:......
Haplotype analysis:for MDD, P-value(odds ratio)=0.461(1.07)
More...
|
No significant asso......
No significant association was observed in MDD.
More...
|
Negative
|
Chen, P.,2011 |
|
rs7090018 - rs11199993 |
T-G |
FGFR2
|
P-value = 0.041, Pe......
P-value = 0.041, Permutated P-value = 0.347
More...
|
No significant asso......
No significant association was found
More...
|
Negative
|
Wang, T.,2012 |
|
rs7090018 - rs11199993 |
T-C |
FGFR2
|
P-value = 0.016, Pe......
P-value = 0.016, Permutated P-value = 0.154
More...
|
No significant asso......
No significant association was found
More...
|
Negative
|
Wang, T.,2012 |
|
rs7090018 - rs11199993 |
G-G |
FGFR2
|
P-value = 0.951, Pe......
P-value = 0.951, Permutated P-value = 1.000
More...
|
No significant asso......
No significant association was found
More...
|
Negative
|
Wang, T.,2012 |
|
rs8007267 - rs378364 - rs841 |
C-T-C |
GCH1
|
Global P-value = 0.......
Global P-value = 0.823,OR(95%CI) = 1.00(1.00-1.00),individual P-value = 0.602
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Kishi, T.,2012(b) |
|
rs8007267 - rs378364 - rs841 |
C-T-T |
GCH1
|
Global P-value = 0.......
Global P-value = 0.823,OR(95%CI) = 1.07(0.871–1.31),P-value = 0.545
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Kishi, T.,2012(b) |
|
rs8007267 - rs378364 - rs841 |
T-A-C |
GCH1
|
Global P-value = 0.......
Global P-value = 0.823,OR(95%CI) = 1.02(0.811–1.28),P-value = 0.998
More...
|
No significant asso......
No significant association was observed.
More...
|
Negative
|
Kishi, T.,2012(b) |
|
rs7090018 - rs11199993 |
G-G |
FGFR2
|
P-value=0.915, Perm......
P-value=0.915, Permutated P-value=1
More...
|
No significant asso......
No significant association was found after permutation.
More...
|
Negative
|
Wang, T.,2012 |
|
rs28536160 - rs28373064 - rs35369693 |
A-G-G |
AVPR1B
|
P-value=0.556, X<......
P-value=0.556, X<sup>2</sup>=0.345
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs28536160 - rs28373064 - rs35369693 |
G-G-G |
AVPR1B
|
P-value=0.352, X<......
P-value=0.352, X<sup>2</sup>=0.865
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs28536160 - rs28373064 - rs35369693 |
G-C-A |
AVPR1B
|
P-value=0.561, X<......
P-value=0.561, X<sup>2</sup>=0.337
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs28536160 - rs28373064 - rs35369693 |
G-G-A |
AVPR1B
|
P-value=0.36, X<......
P-value=0.36, X<sup>2</sup>=0.837
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs4792887 - rs110402 |
C-A |
CRHR1
|
P-value=0.071, X<......
P-value=0.071, X<sup>2</sup>=3.251
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs4792887 - rs110402 |
C-G |
CRHR1
|
P-value=0.288, X<......
P-value=0.288, X<sup>2</sup>=1.129
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs4792887 - rs110402 |
T-G |
CRHR1
|
P-value=0.211, X<......
P-value=0.211, X<sup>2</sup>=1.559
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 |
C-C-G-C-C |
CRHR1
|
P-value=0.75, X<......
P-value=0.75, X<sup>2</sup>=0.101
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 |
C-T-A-C-G |
CRHR1
|
P-value=0.297, X<......
P-value=0.297, X<sup>2</sup>=1.086
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 |
C-C-A-T-C |
CRHR1
|
P-value=0.306, X<......
P-value=0.306, X<sup>2</sup>=1.048
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 |
C-C-A-C-C |
CRHR1
|
P-value=0.454, X<......
P-value=0.454, X<sup>2</sup>=0.557
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 |
T-C-A-C-C |
CRHR1
|
P-value=0.278, X<......
P-value=0.278, X<sup>2</sup>=1.175
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies.
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 |
C-C-A-C-G |
CRHR1
|
P-value=0.031, X<......
P-value=0.031, X<sup>2</sup>=4.626
More...
|
For the MDD and bip......
For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. We observed that the CCACG haplotype in the second haplotype block was significantly more frequent in the patients with mood disorders than in healthy individuals (P=0.031); however, the difference was not observed after multiple testing correction (after 10 000 permutations, P=0.208).
More...
|
Negative
|
Szczepankiewicz, A., 2013 |
|
rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 |
A-C-G-C-C-A-C |
FKBP5
|
|
rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 |
C-C-A-T-T-G-T |
FKBP5
|
|
rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 |
C-T-A-C-T-G-T |
FKBP5
|
|
rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 |
A-C-G-C-C-G-T |
FKBP5
|
|
rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 |
C-C-A-C-T-G-T |
FKBP5
|
|