GO Report

Basic Info

ID	GO:0003677
Name	DNA binding
Type	molecular function
No. of Genes in BDgene	83
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
GO:03677: DNA binding	PBA paper	Holmans, P., 2009	WTCCC+STEP-UCL+ED-DUB-STEP2	ALIGATOR (Association LIst Go AnnoTatOR)	FUNCTION, cutoff for significant SNPs: p < 0.01

GO related genes in BDgene (count: 83)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
RNF4	ring finger protein 4	4p16.3	1(0/0/1)	ISS
SCML4	sex comb on midleg-like 4 (Drosophila)	6q21	1(0/1/0)	IEA
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11p15	7(5/2/0)	IDA[11441146]; IGI[9576906]
ZNF563	zinc finger protein 563	19p13.2	1(0/0/1)	IEA
TAL2	T-cell acute lymphocytic leukemia 2	9q32	1(0/0/1)	IEA
ZBTB20	zinc finger and BTB domain containing 20	3q13.2	1(0/1/0)	IEA
ZNF74	zinc finger protein 74	22q11.2	1(0/1/0)	IEA
TCF4	transcription factor 4	18q21.1	6(1/5/0)	IDA[1681116]
KAT6B	K(lysine) acetyltransferase 6B	10q22.2	1(1/0/0)	IEA
NPAS3	neuronal PAS domain protein 3	14q13.1	2(1/1/0)	IEA
ZBED4	zinc finger, BED-type containing 4	22q13.33	1(1/0/0)	IEA
FOXO3	forkhead box O3	6q21	1(1/0/0)	IDA[21329882]
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	5q14.2	1(0/1/0)	IDA[9259561]
CERS3	ceramide synthase 3	15q26.3	1(0/0/1)	IEA
CDKN2A	cyclin-dependent kinase inhibitor 2A	9p21	1(1/0/0)	IEA
INO80	INO80 complex subunit	15q15.1	1(0/1/0)	IDA[16298340]
POLN	polymerase (DNA directed) nu	4p16.3	1(0/0/1)	IEA
ZNF732	zinc finger protein 732	4p16.3	1(0/0/1)	IEA
SP4	Sp4 transcription factor	7p15	1(1/0/0)	IEA
TFIP11	tuftelin interacting protein 11	22q12.1	1(1/0/0)	IEA
SURF6	surfeit 6	9q33-q34	1(0/1/0)	ISS
ZNF678	zinc finger protein 678	1q42.13	1(0/1/0)	IEA
EGR3	early growth response 3	8p23-p21	3(2/1/0)	IEA
PALB2	partner and localizer of BRCA2	16p12.1	5(2/2/1)	IDA[20871616]
GSC2	goosecoid homeobox 2	22q11.21	1(0/1/0)	TAS[9441739]
ZNF284	zinc finger protein 284	19q13.32	1(1/0/0)	IEA
NCOR2	nuclear receptor corepressor 2	12q24	1(0/1/0)	IEA
ARID1B	AT rich interactive domain 1B (SWI1-like)	6q25.3	1(0/0/1)	IEA
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	2q24.2	1(0/1/0)	IEA
CRY1	cryptochrome circadian clock 1	12q23-q24.1	2(1/1/0)	TAS[9801304]
XBP1	X-box binding protein 1	22q12.1	3(2/1/0)	TAS[1718857]
ZHX2	zinc fingers and homeoboxes 2	8q24.13	1(0/0/1)	IEA
HNF4A	hepatocyte nuclear factor 4, alpha	20q13.12	1(1/0/0)	IDA[10551874]
TSNAX	translin-associated factor X	1q42.2	4(3/1/0)	TAS[9013868]
ZNF236	zinc finger protein 236	18q22-q23	1(1/0/0)	IEA
AHRR	aryl-hydrocarbon receptor repressor	5p15.33	1(1/0/0)	IEA
TRIM26	tripartite motif containing 26	6p21.3	2(2/0/0)	NAS[8530076]
NFIL3	nuclear factor, interleukin 3 regulated	9q22	2(0/2/0)	TAS[1620116]
ARNT2	aryl-hydrocarbon receptor nuclear translocator 2	15q25.1	1(0/1/0)	IEA
HES1	hes family bHLH transcription factor 1	3q28-q29	1(0/1/0)	TAS[7906273]
PPARD	peroxisome proliferator-activated receptor delta	6p21.2	1(1/0/0)	ISS
ZNF490	zinc finger protein 490	19p13.2	1(1/0/0)	IEA
FBXO18	F-box protein, helicase, 18	10p15.1	1(1/0/0)	IEA
CHD1L	chromodomain helicase DNA binding protein 1-like	1q21.1	1(1/0/0)	IEA
ZNF680	zinc finger protein 680	7q11.21	1(0/0/1)	IEA
ZIC2	Zic family member 2	13q32	1(0/1/0)	ISS
MYT1L	myelin transcription factor 1-like	2p25.3	1(1/0/0)	IEA
CLOCK	clock circadian regulator	4q12	12(5/7/0)	IDA[11441146]
PAX8	paired box 8	2q13	1(0/0/1)	IDA[15961562]; IMP[9590296]
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	19p13.3	4(0/3/1)	IEA
EGR1	early growth response 1	5q23-q31	1(0/1/0)	IDA[12560508]
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	11p15.4	1(0/1/0)	IEA
AHR	aryl hydrocarbon receptor	7p15	1(1/0/0)	IDA[15681594]; TAS[19538249]
ATF4	activating transcription factor 4	22q13.1	1(1/0/0)	IDA[15788408]; ISS
ATXN1	ataxin 1	6p23	2(1/1/0)	IEA
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	6p12	1(0/1/0)	TAS[12072434]
FOXP2	forkhead box P2	7q31	2(0/2/0)	IDA[16407075]
HMG20A	high mobility group 20A	15q24	1(1/0/0)	NAS[10773667]
ZKSCAN4	zinc finger with KRAB and SCAN domains 4	6p21	1(1/0/0)	IEA
PHF20	PHD finger protein 20	20q11.22-q11.23	1(0/1/0)	IEA
SP8	Sp8 transcription factor	7p21.2	3(2/0/1)	IEA
PRIM2	primase, DNA, polypeptide 2 (58kDa)	6p12-p11.1	1(0/0/1)	IEA
ZSCAN31	zinc finger and SCAN domain containing 31	6p	1(1/0/0)	IEA
HMGXB4	HMG box domain containing 4	22q13	1(1/0/0)	IEA
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	2p11.2	1(0/1/0)	NAS[11085512]
EGR4	early growth response 4	2p13	1(0/1/0)	IEA
RORA	RAR-related orphan receptor A	15q21-q22	3(2/1/0)	IDA[11053433]
ZNF626	zinc finger protein 626	19p13.11	1(0/0/1)	IEA
GTF3C5	general transcription factor IIIC, polypeptide 5, 63kDa	9q34.13	1(0/1/0)	IC[17409385]
YY1	YY1 transcription factor	14q	1(0/1/0)	IDA[21729784]
CRY2	cryptochrome circadian clock 2	11p11.2	5(3/2/0)	IDA[12627958]
RAD51B	RAD51 paralog B	14q23-q24.2	1(0/1/0)	TAS[9512535]
POU6F2	POU class 6 homeobox 2	7p14.1	1(1/0/0)	IEA
PBRM1	polybromo 1	3p21	5(4/0/1)	IEA
RLF	rearranged L-myc fusion	1p32	1(0/1/0)	NAS[8545128]
GFI1B	growth factor independent 1B transcription repressor	9q34.13	1(0/1/0)	IEA
POLE2	polymerase (DNA directed), epsilon 2, accessory subunit	14q21-q22	1(1/0/0)	IEA
SOD2	superoxide dismutase 2, mitochondrial	6q25	2(1/1/0)	IEA
LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2q37.3	1(0/1/0)	IDA[23099021]
IRF2	interferon regulatory factor 2	4q34.1-q35.1	1(1/0/0)	IDA[9540062]
EBF1	early B-cell factor 1	5q34	1(1/0/0)	IEA
NPAS2	neuronal PAS domain protein 2	2q11.2	5(3/2/0)	IDA[11441146]; IPI[9576906]
CREM	cAMP responsive element modulator	10p12.1-p11.1	1(0/1/0)	NAS[7916662]