Gene Report

Basic Info
Approved Symbol HMGXB4
Previous Symbol HMG2L1
Symbol Alias THC211630
Approved Name HMG box domain containing 4
Previous Name high-mobility group protein 2-like 1
Location 22q13
Position chr22:35257452-35295807, 1
External Links HGNC: 5003
Entrez Gene: 10042
Ensembl: ENSG00000100281
UCSC: uc003anl.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Potash, J. B., 2008 SNP: rs2038010, rs2413338, rs713770, rs932290 Permutation of genotypewise results for rs2413338 in HMG2L1 showed an empirical P=0.037 for the difference between subsets.. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 8)

GO terms by PBA (count: 1)

GO terms by database search (count: 7)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 41)

Literature-origin SNPs (count: 4)

LD-proxies (count: 37)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr22:35257452..35295807 View in gBrowse
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