Gene Report

Basic Info
Approved Symbol ZNF74
Symbol Alias Cos52, Zfp520, ZNF520
Approved Name zinc finger protein 74
Previous Name zinc finger protein 74 (Cos52)
Location 22q11.2
Position chr22:20394115-20408461, 1
External Links HGNC: 13144
Entrez Gene: 7625
Ensembl: ENSG00000185252
UCSC: uc010gsm.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 3 SNP typed, Median D'=0.96, Median r<sup>2</sup> =0.46, 1 LD blocks, 0.51 block coverage, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA.. This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 9)

GO terms by PBA (count: 3)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 3)

Gene relationship with MDD

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Region: chr22:20394115..20408461 View in gBrowse
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