Gene Report

Basic Info
Approved Symbol EGR1
Symbol Alias TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225
Approved Name early growth response 1
Name Alias nerve growth factor-induced protein A, "transcription factor ETR103", "zinc finger protein 225", "early growth response protein 1"
Location 5q23-q31
Position chr5:138465490-138469315, 1
External Links HGNC: 3238
Entrez Gene: 1958
Ensembl: ENSG00000120738
UCSC: uc003ldb.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gallitano, A. L.,2012 SNP: rs11741807, rs11743810, rs1548587, rs1800778, rs2051861, rs6914, rs7729723 None of the SNPs tested in EGR1 was associated with child BP-I. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 58)

GO terms by PBA (count: 4)

GO terms by database search (count: 54)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 12)

Related other genetic factors
Gene related SNPs (count: 9)

Literature-origin SNPs (count: 7)

LD-proxies (count: 2)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 3)

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Region: chr5:138465490..138469315 View in gBrowse
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