BDgene

Gene Report

Basic Info
Approved Symbol IRF2
Approved Name interferon regulatory factor 2
Location 4q34.1-q35.1
Position chr4:184387713-184474580, -1
External Links HGNC: 6117
Entrez Gene: 3660
Ensembl: ENSG00000168310
UCSC: uc003iwf.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Hattori, E.,2009 SNP: rs3775552 After the two-stage analysis, markers in this gene remained nominally significant (allelic P<0.05) with the same allele being consistently over-represented in both the first and the follow-up stages. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 18)

GO terms by PBA (count: 2)

GO terms by database search (count: 16)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 11)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 1)

LD-proxies (count: 2)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)


View in gBrowse

Region: chr4:184387713..184474580 View in gBrowse
View in gBrowse