Gene Report

Basic Info
Approved Symbol CDKN2A
Previous Symbol CDKN2, MLM
Symbol Alias CDK4I, p16, INK4a, MTS1, CMM2, ARF, p19, p14, INK4, p16INK4a, p19Arf, p14ARF
Approved Name cyclin-dependent kinase inhibitor 2A
Previous Name cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
Location 9p21
Position chr9:21967753-21995301, -1
External Links HGNC: 1787
Entrez Gene: 1029
Ensembl: ENSG00000147889
UCSC: uc003zpk.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Moskvina, V.,2009 In BD:Smallest P-value per gene=0.0063, Product of P truncation <=0.01=0.0063, Product of P truncation <=0.001=NA. It showed evidence for association with BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 66)

GO terms by PBA (count: 2)

GO terms by database search (count: 64)

Gene related KEGG pathways (count: 8)

KEGG pathways by PBA (count: 4)

KEGG pathways by database search (count: 4)

Gene related BioCarta pathways (count: 4)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 4)

Gene related interactors from protein-protein interactions data in HPRD (count: 39)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr9:21967753..21995301 View in gBrowse
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