Gene Report

Basic Info
Approved Symbol NFIL3
Previous Symbol IL3BP1
Symbol Alias E4BP4, NFIL3A, NF-IL3A
Approved Name nuclear factor, interleukin 3 regulated
Location 9q22
Position chr9:91409045-91423862, -1
External Links HGNC: 7787
Entrez Gene: 4783
Ensembl: ENSG00000165030
UCSC: uc004arh.3
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Byrne, E. M., 2014 P-value=0.19. Gene-based tests show no significant association between this gene and BD. Negative Comment on Study
Mansour, H. A.,2009 Gene-based tests:X<sup>2</sup>=3.129, P-value = 0.448 in dominant model, X<sup>2</sup>=2.497, P-value = 0.575 in additive model, X<sup>2</sup>=2.136, P-value = 0.699 in recessive model in BPI. No significant association was observed using neither single SNP-based analyses nor gene-based tests in BPI. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 14)

GO terms by PBA (count: 4)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 2)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

View in gBrowse

Region: chr9:91409045..91423862 View in gBrowse
View in gBrowse