Gene Report

Basic information

Related studies

Functional annotation

Related other genetic factors

Overlap with SZ and MDD

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Basic Info

Approved Symbol	BAZ2B
Symbol Alias	WALp4
Approved Name	bromodomain adjacent to zinc finger domain, 2B
Location	2q24.2
Position	chr2:159318979-159616692, -1
External Links	HGNC: 963 Entrez Gene: 29994 Ensembl: ENSG00000123636 UCSC: uc002uao.3
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs3821298	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

GO terms by PBA (count: 2)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005634	nucleus	cellular component	IEA	283
GO:0003677	DNA binding	molecular function	IEA	83

GO terms by database search (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0006355	regulation of transcription, DNA-templated	biological process	NAS[10662543]	62
GO:0008270	zinc ion binding	molecular function	IEA	77
GO:0006351	transcription, DNA-templated	biological process	NAS[10662543]	103
GO:0005515	protein binding	molecular function	IPI[10662543]	563

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Gene	Interactor	Interactor in BDgene?	Experiment Type	PMID
BAZ2B	CTBP2	YES	yeast 2-hybrid	16189514

Related other genetic factors

Gene related SNPs (count: 31)

Literature-origin SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs3821298	chr2:159430008 - 159430008(1)	intron_variant; non_coding_transcript_variant	1(0/1/0)

LD-proxies (count: 30)

rs_ID	Location	Functional Annotation
rs12470533	chr2:159448230 - 159448230(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs17423523	chr2:159449301 - 159449301(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs2193923	chr2:159441612 - 159441612(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs2193924	chr2:159445841 - 159445841(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs12624147	chr2:159437018 - 159437018(1)	downstream_gene_variant; intron_variant; upstream_gene_variant
rs12474624	chr2:159440061 - 159440061(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs741	chr2:159434554 - 159434554(1)	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant
rs13033860	chr2:159436422 - 159436422(1)	downstream_gene_variant; intron_variant; upstream_gene_variant
rs1346013	chr2:159456829 - 159456829(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs12473369	chr2:159459636 - 159459636(1)	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant
rs17495453	chr2:159451072 - 159451072(1)	intron_variant; non_coding_transcript_variant
rs13026780	chr2:159456400 - 159456400(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs12988312	chr2:159449380 - 159449380(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs12988336	chr2:159449408 - 159449408(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs13028985	chr2:159402747 - 159402747(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs2193922	chr2:159399817 - 159399817(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs1549115	chr2:159419329 - 159419329(1)	intron_variant; non_coding_transcript_variant
rs12470244	chr2:159416548 - 159416548(1)	intron_variant; non_coding_transcript_variant
rs2302927	chr2:159382867 - 159382867(1)	downstream_gene_variant; intron_variant; upstream_gene_variant
rs7583758	chr2:159355060 - 159355060(1)	intron_variant
rs3771712	chr2:159396057 - 159396057(1)	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant
rs12995487	chr2:159392606 - 159392606(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs3755436	chr2:159426272 - 159426272(1)	intron_variant; non_coding_transcript_variant
rs1023603	chr2:159424835 - 159424835(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs12473781	chr2:159429064 - 159429064(1)	intron_variant; non_coding_transcript_variant
rs3755437	chr2:159426465 - 159426465(1)	intron_variant; non_coding_transcript_variant
rs3771717	chr2:159420665 - 159420665(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs3771716	chr2:159419732 - 159419732(1)	intron_variant; non_coding_transcript_variant
rs13022220	chr2:159422919 - 159422919(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs4664286	chr2:159421898 - 159421898(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
2q24	chr2:154000000-168900000	4 (0/3/1)
2q21-q33	chr2:129100000-208200000	1 (0/0/1)
Chr 2	chr2:0-242193529	3 (0/3/0)
2q24-33	chr2:154000000-208200000	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:159318979..159616692 View in gBrowse