Region Report

Basic Info

Region Name	Chr 2
Chromosome Position	chr2:0-242193529
No. of Studies (Positive/Negative/Trend)	3(0/3/0)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Avramopoulos, D., 2007	D2S151 (BPI, BPII), D2S347 (BPI, restricted)	P-value = 0.021, NPL = 2.05, Dominant Max HLOD = 1.43, Re...... P-value = 0.021, NPL = 2.05, Dominant Max HLOD = 1.43, Recessive Max HLOD = 0.46 in Ashkenazi pedigrees; P-value = 0.03, NPL = 1.9, Dominant Max HLOD = 0.58, Recessive Max HLOD = 0.96 in BPI-restricted pedigrees More...	the absolute value of the resulting scores remained moderate the absolute value of the resulting scores remained moderate	Negative
Murphy, V. E.,2000	D2S390	Linkage analysis: broad model, NPL = -0.113, P-value = 0.55;...... Linkage analysis: broad model, NPL = -0.113, P-value = 0.55; narrow model, NPL = 0.288, P-value = 0.32 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Badner, J. A.,2002		Meta analysis: Location: 133, Single Analysis MSP = 0.04, Be...... Meta analysis: Location: 133, Single Analysis MSP = 0.04, Best Analysis MSP = 0.06 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 83)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
B3GALT1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	2q24.3	1(1/0/0)
TP53I3	tumor protein p53 inducible protein 3	2p23.3	1(1/0/0)
XIRP2	xin actin-binding repeat containing 2	2q31.1	1(0/1/0)
ITGB6	integrin, beta 6	2q24.2	1(1/0/0)
NCKAP5	NCK-associated protein 5	2q21.2	1(0/0/1)
SPAG16	sperm associated antigen 16	2q34	1(0/1/0)
TRAPPC12	trafficking protein particle complex 12	2p25.3	1(0/0/1)
NCK2	NCK adaptor protein 2	2q12	1(1/0/0)
AHSA2	AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)	2p14	1(0/0/1)
SLC20A1	solute carrier family 20 (phosphate transporter), member 1	2q13	1(0/1/0)
INHBB	inhibin, beta B	2q14.2	1(0/1/0)
CHN1	chimerin 1	2q31-q32.1	1(0/0/1)
BCL2L11	BCL2-like 11 (apoptosis facilitator)	2q13	1(0/1/0)
NTSR2	neurotensin receptor 2	2p25.1	1(1/0/0)
NT5DC4	5'-nucleotidase domain containing 4	2q13	1(0/0/1)
EVA1A	eva-1 homolog A (C. elegans)	2p12	1(1/0/0)
SNTG2	syntrophin, gamma 2	2p25	1(0/0/1)
SPATS2L	spermatogenesis associated, serine-rich 2-like	2q33.1	1(1/0/0)
VRK2	vaccinia related kinase 2	2p16.1	1(0/1/0)
LOC100533709	piggyBac transposable element derived 2 pseudogene		1(0/1/0)
CAMKMT	calmodulin-lysine N-methyltransferase	2p21	1(0/0/1)
LINC00607	long intergenic non-protein coding RNA 607	2q35	1(0/0/1)
PER2	period circadian clock 2	2q37.3	7(1/6/0)
GALNT13	polypeptide N-acetylgalactosaminyltransferase 13	2q24.1	1(0/1/0)
RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	2q37.3	2(1/0/1)
DPP10	dipeptidyl-peptidase 10 (non-functional)	2q14.1	3(2/1/0)
GAD1	glutamate decarboxylase 1 (brain, 67kDa)	2q31	2(1/1/0)
LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2q37.3	1(0/1/0)
SPR	sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)	2p14-p12	1(1/0/0)
DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	2q21.2	2(0/2/0)
ERBB4	erb-b2 receptor tyrosine kinase 4	2q33.3-q34	2(1/1/0)
CAPN10	calpain 10	2q37.3	1(1/0/0)
STK39	serine threonine kinase 39	2q24.3	2(0/2/0)
NR4A2	nuclear receptor subfamily 4, group A, member 2	2q22-q23	1(0/1/0)
CHCHD5	coiled-coil-helix-coiled-coil-helix domain containing 5	2q14.1	1(0/1/0)
ACOXL	acyl-CoA oxidase-like	2q13	2(0/2/0)
NRXN1	neurexin 1	2p16.3	1(1/0/0)
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	2p16.1	1(1/0/0)
ZNF804A	zinc finger protein 804A	2q32.1	6(3/3/0)
THSD7B	thrombospondin, type I, domain containing 7B	2q22.1	1(1/0/0)
MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	2q12	1(0/0/1)
SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	2p15-p13	1(0/1/0)
LIMS2	LIM and senescent cell antigen-like domains 2	2q21.1	1(1/0/0)
STEAP3	STEAP family member 3, metalloreductase	2q14.2	1(0/0/1)
LPIN1	lipin 1	2p25.1	1(0/0/1)
TACR1	tachykinin receptor 1	2p13.1-p12	3(3/0/0)
INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	2q11.2	1(0/0/1)
EDAR	ectodysplasin A receptor	2q13	1(0/1/0)
PRKCE	protein kinase C, epsilon	2p21	1(0/1/0)
MARCO	macrophage receptor with collagenous structure	2q14.2	1(0/1/0)
RTN4	reticulon 4	2p16.1	1(0/1/0)
CNTNAP5	contactin associated protein-like 5	2q14.1	2(0/2/0)
GLI2	GLI family zinc finger 2	2q14	1(0/1/0)
WIPF1	WAS/WASL interacting protein family, member 1	2q31.2	1(0/0/1)
HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	2q32.3	1(0/0/1)
CREB1	cAMP responsive element binding protein 1	2q34	2(1/1/0)
IL1B	interleukin 1, beta	2q14	1(1/0/0)
NPAS2	neuronal PAS domain protein 2	2q11.2	5(3/2/0)
INPP1	inositol polyphosphate-1-phosphatase	2q32	1(0/1/0)
PLA2R1	phospholipase A2 receptor 1, 180kDa	2q23-q24	1(1/0/0)
APOB	apolipoprotein B	2p24-p23	1(0/0/1)
MYT1L	myelin transcription factor 1-like	2p25.3	1(1/0/0)
PFN4	profilin family, member 4	2p24.1	1(1/0/0)
CTLA4	cytotoxic T-lymphocyte-associated protein 4	2q33	2(1/1/0)
TTC27	tetratricopeptide repeat domain 27	2p22.3	1(1/0/0)
EGR4	early growth response 4	2p13	1(0/1/0)
SCN7A	sodium channel, voltage gated, type VII alpha subunit	2q21-q23	1(0/1/0)
GAPDHP57	glyceraldehyde 3 phosphate dehydrogenase pseudogene 57	2p12	1(1/0/0)
SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	2p23.1	1(0/1/0)
SH3RF3	SH3 domain containing ring finger 3	2q13	1(0/0/1)
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	2p21	1(0/1/0)
KCNH7	potassium channel, voltage gated eag related subfamily H, member 7	2q24.3	3(2/0/1)
CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)	2q31.1	2(0/1/1)
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	2p11.2	1(0/1/0)
PAX8	paired box 8	2q13	1(0/0/1)
MALL	mal, T-cell differentiation protein-like	2q13	1(0/1/0)
LMAN2L	lectin, mannose-binding 2-like	2q11.1	2(2/0/0)
BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	2p23	1(0/1/0)
CCDC148	coiled-coil domain containing 148	2q24.1	1(0/1/0)
ARHGAP15	Rho GTPase activating protein 15	2q22.2-q22.3	1(0/1/0)
CNNM4	cyclin and CBS domain divalent metal cation transport mediator 4	2q11.2	1(1/0/0)
IL1RN	interleukin 1 receptor antagonist	2q14.2	2(2/0/0)
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	2q24.2	1(0/1/0)

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Region: chr2:0..242193529 View in gBrowse