Gene Report

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Basic Info

Approved Symbol	B3GALT1
Symbol Alias	beta3Gal-T1
Approved Name	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
Location	2q24.3
Position	chr2:167868948-167874041, 1
External Links	HGNC: 916 Entrez Gene: 8708 Ensembl: ENSG00000172318 UCSC: uc002udz.1
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0030. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	NAS[9582303]	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	molecular function	IDA[9582303]	2
GO:0006486	protein glycosylation	biological process	IDA[9582303]; IEA	5
GO:0009312	oligosaccharide biosynthetic process	biological process	IEA	1
GO:0000139	Golgi membrane	cellular component	IEA	36

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in BDgene	Brief Description
hsa00601	Glycosphingolipid biosynthesis - lactoseries	2

ID	Name	No. of Genes in BDgene	Brief Description
hsa01031	Glycan structures - biosynthesis 2	3

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
2q24.3	chr2:162900000-168900000	1 (0/0/1)
2q24	chr2:154000000-168900000	4 (0/3/1)
2q21-q33	chr2:129100000-208200000	1 (0/0/1)
Chr 2	chr2:0-242193529	3 (0/3/0)
2q24-33	chr2:154000000-208200000	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:167868948..167874041 View in gBrowse