Gene Report

Basic Info
Approved Symbol LIMS2
Approved Name LIM and senescent cell antigen-like domains 2
Location 2q21.1
Position chr2:127638381-127681786, -1
External Links HGNC: 16084
Entrez Gene: 55679
Ensembl: ENSG00000072163
UCSC: uc010yzm.2
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Drago, A., 2016 Freq(Significant SNPs/total SNPs%)=0.02. Encodes for member of a small family of focal adhesion proteins and is involved in the modulation of cell spreading and migration. This adapter protein links beta-integrins to the actin cytoskeleton, and bridges this cytoplasmic complex to cell surface receptor tyrosine kinases and growth factor receptors. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 2)

GO terms by database search (count: 11)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:127638381..127681786 View in gBrowse
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