Gene Report

Basic Info
Approved Symbol NCK2
Symbol Alias NCKbeta
Approved Name NCK adaptor protein 2
Location 2q12
Position chr2:105744897-105894274, 1
External Links HGNC: 7665
Entrez Gene: 8440
Ensembl: ENSG00000071051
UCSC: uc002tdi.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Drago, A., 2016 Freq(Significant SNPs/total SNPs%)=0.21. Encodes for an adapter protein of NCK family which plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 27)

GO terms by PBA (count: 2)

GO terms by database search (count: 25)

Gene related KEGG pathways (count: 5)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 5)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 34)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr2:105744897..105894274 View in gBrowse
View in gBrowse