Gene Report

Basic Info
Approved Symbol SCN7A
Previous Symbol SCN6A
Symbol Alias Nav2.1, Nav2.2, NaG
Approved Name sodium channel, voltage gated, type VII alpha subunit
Previous Name sodium channel, voltage-gated, type VI, alpha, "sodium channel, voltage-gated, type VII, alpha", "sodium channel, voltage-gated, type VII, alpha subunit"
Location 2q21-q23
Position chr2:166403573-166494247, -1
External Links HGNC: 10594
Entrez Gene: 6332
Ensembl: ENSG00000136546
UCSC: uc002udu.2
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs1172384, rs12475889, rs6738031, rs7565062, rs7597971 A number of genes with no previous association to BD have multiple SNPs with suggestive association, including the brain-expressed gene SCN7A. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 11)

GO terms by PBA (count: 2)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 15)

Literature-origin SNPs (count: 5)

LD-proxies (count: 10)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:166403573..166494247 View in gBrowse
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