BDgene

Gene Report

Basic Info
Approved Symbol SCN7A
Previous Symbol SCN6A
Symbol Alias Nav2.1, Nav2.2, NaG
Approved Name sodium channel, voltage gated, type VII alpha subunit
Previous Name sodium channel, voltage-gated, type VI, alpha, "sodium channel, voltage-gated, type VII, alpha", "sodium channel, voltage-gated, type VII, alpha subunit"
Location 2q21-q23
Position chr2:166403573-166494247, -1
External Links HGNC: 10594
Entrez Gene: 6332
Ensembl: ENSG00000136546
UCSC: uc002udu.2
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs1172384, rs12475889, rs6738031, rs7565062, rs7597971 A number of genes with no previous association to BD have multiple SNPs with suggestive association, including the brain-expressed gene SCN7A. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 11)

GO terms by PBA (count: 2)

GO terms by database search (count: 9)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 15)

Literature-origin SNPs (count: 5)

LD-proxies (count: 10)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:166403573..166494247 View in gBrowse
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