Gene Report

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Basic Info

Approved Symbol	SPATS2L
Symbol Alias	DNAPTP6
Approved Name	spermatogenesis associated, serine-rich 2-like
Name Alias	DNA polymerase transactivated protein 6
Location	2q33.1
Position	chr2:200305881-200482263, 1
External Links	HGNC: 24574 Entrez Gene: 26010 Ensembl: ENSG00000196141 UCSC: uc010zhc.2
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0004. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005634	nucleus	cellular component	IDA	283

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0043234	protein complex	cellular component	IDA	27
GO:0044822	poly(A) RNA binding	molecular function	IDA[22658674]	44
GO:0005737	cytoplasm	cellular component	IDA	322
GO:0005730	nucleolus	cellular component	IDA	28

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
2q21-q33	chr2:129100000-208200000	1 (0/0/1)
Chr 2	chr2:0-242193529	3 (0/3/0)
2q24-33	chr2:154000000-208200000	1 (1/0/0)
2q32.3-q33	chr2:191100000-208200000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr2:200305881..200482263 View in gBrowse