Gene Report

Basic Info
Approved Symbol RNPEPL1
Approved Name arginyl aminopeptidase (aminopeptidase B)-like 1
Location 2q37.3
Position chr2:240565804-240581372, 1
External Links HGNC: 10079
Entrez Gene: 57140
Ensembl: ENSG00000142327
UCSC: uc002vzi.4
No. of Studies 2 (Positive: 1; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Moskvina, V.,2009 In BP:Smallest P-value per gene=0.00005, Product of P truncation <=0.01=0.00001, Product of P truncation <=0.001=0.00001. It showed evidence for association with BD. Positive Comment on Study
Feng, T.,2010 SNP: rs6730107 This gene showed moderate association evidence. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 5)

GO terms by PBA (count: 1)

GO terms by database search (count: 4)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 6)

Literature-origin SNPs (count: 4)

LD-proxies (count: 2)

Gene related CNVs (count: 2)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr2:240565804..240581372 View in gBrowse
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