Region Report

Basic Info

Region Name	Chr 7
Chromosome Position	chr7:0-159345973
No. of Studies (Positive/Negative/Trend)	3(0/3/0)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Murphy, V. E.,2000	D7S632	Linkage analysis: broad model, NPL = 0.123, P-value = 0.44; ...... Linkage analysis: broad model, NPL = 0.123, P-value = 0.44; narrow model, NPL = -0.097, P-value = 0.56 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Avramopoulos, D., 2007	D7S531 (BPI, BPII), D7S636 (BPI, restricted)	P-value = 0.028, NPL = 1.91, Dominant Max HLOD = 0.19, Re...... P-value = 0.028, NPL = 1.91, Dominant Max HLOD = 0.19, Recessive Max HLOD = 0.53 in Ashkenazi pedigrees; P-value = 0.037, NPL = 1.81, Dominant Max HLOD = 0.45, Recessive Max HLOD = 0.6 in BPI-restricted pedigrees More...	the absolute value of the resulting scores remained moderate the absolute value of the resulting scores remained moderate	Negative
Badner, J. A.,2002		Meta analysis: Location: 17(116), Single Analysis MSP = 0.01...... Meta analysis: Location: 17(116), Single Analysis MSP = 0.01, Best Analysis MSP = 0.01 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 93)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TCAF1	TRPM8 channel-associated factor 1	7q35	1(1/0/0)
EGFR	epidermal growth factor receptor	7p12	1(0/0/1)
ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5	7q35	1(1/0/0)
JAZF1	JAZF zinc finger 1	7p15.2-p15.1	1(0/1/0)
THSD7A	thrombospondin, type I, domain containing 7A	7p21.3	1(1/0/0)
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	7q31.3	1(1/0/0)
ZNF277	zinc finger protein 277	7q31.1	1(1/0/0)
COBL	cordon-bleu WH2 repeat protein	7p12.2-p12.1	1(1/0/0)
TRIM24	tripartite motif containing 24	7q32-q34	1(1/0/0)
ZNF680	zinc finger protein 680	7q11.21	1(0/0/1)
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	7q35-q36	1(1/0/0)
CHN2	chimerin 2	7p15.3	1(1/0/0)
PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2	7q36	1(0/0/1)
RELN	reelin	7q22	3(1/2/0)
CDK13	cyclin-dependent kinase 13	7p14.1	1(1/0/0)
AHR	aryl hydrocarbon receptor	7p15	1(1/0/0)
HOXA3	homeobox A3	7p15.2	1(1/0/0)
HTR5A	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled	7q36.1	2(1/1/0)
SP4	Sp4 transcription factor	7p15	1(1/0/0)
VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1	7q11.21	1(1/0/0)
HDAC9	histone deacetylase 9	7p21.1	1(1/0/0)
CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	7q21-q22	2(0/0/2)
PPP1R9A	protein phosphatase 1, regulatory subunit 9A	7q21.3	1(0/0/1)
CROT	carnitine O-octanoyltransferase	7q21.1	1(0/0/1)
NAMPT	nicotinamide phosphoribosyltransferase	7q22.3	1(1/0/0)
ABCA13	ATP-binding cassette, sub-family A (ABC1), member 13	7p12.3	2(2/0/0)
CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3	7q33	1(0/1/0)
SAMD9L	sterile alpha motif domain containing 9-like	7q21.2	1(0/0/1)
IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	7q31	1(1/0/0)
CRHR2	corticotropin releasing hormone receptor 2	7p14.3	3(2/1/0)
GLI3	GLI family zinc finger 3	7p13	1(1/0/0)
SYPL1	synaptophysin-like 1	7q22.2	1(1/0/0)
UPP1	uridine phosphorylase 1	7p12.3	1(1/0/0)
ZAN	zonadhesin (gene/pseudogene)	7q22.1	1(0/0/1)
DPP6	dipeptidyl-peptidase 6	7q36.2	2(1/1/0)
CHRM2	cholinergic receptor, muscarinic 2	7q35-q36	1(0/1/0)
EXOC4	exocyst complex component 4	7q31	1(0/0/1)
CUL1	cullin 1	7q36.1	1(1/0/0)
HEPACAM2	HEPACAM family member 2	7q21.3	1(0/0/1)
KMT2E	lysine (K)-specific methyltransferase 2E	7q22.1	1(0/0/1)
UPK3B	uroplakin 3B	7q11.2	1(0/0/1)
UFSP1	UFM1-specific peptidase 1 (non-functional)	7q22.1	1(0/0/1)
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7p22	1(1/0/0)
SNX13	sorting nexin 13	7p21.1	1(1/0/0)
AKR1D1	aldo-keto reductase family 1, member D1	7q32-q33	2(0/1/1)
LHFPL3	lipoma HMGIC fusion partner-like 3	7q22.2	1(0/1/0)
DPY19L1	dpy-19-like 1 (C. elegans)	7p14.3-p14.2	1(0/0/1)
SAMD9	sterile alpha motif domain containing 9	7q21.2	1(0/0/1)
SDK1	sidekick cell adhesion molecule 1	7p22.3	1(1/0/0)
MEOX2	mesenchyme homeobox 2	7p22.1-p21.3	1(1/0/0)
CDHR3	cadherin-related family member 3	7q22.2	1(0/1/0)
ACTR3B	ARP3 actin-related protein 3 homolog B (yeast)	7q36.1	1(0/0/1)
ATXN7L1	ataxin 7-like 1	7q22.1	1(1/0/0)
PON1	paraoxonase 1	7q21.3	2(2/0/0)
NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D	7q22.1	1(1/0/0)
WDR60	WD repeat domain 60	7q36.3	1(0/1/0)
AUTS2	autism susceptibility candidate 2	7q11.22	1(1/0/0)
PILRA	paired immunoglobin-like type 2 receptor alpha	7q22.1	1(0/0/1)
GNA12	guanine nucleotide binding protein (G protein) alpha 12	7p22.3	1(1/0/0)
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1	7q21.12	1(1/0/0)
KCND2	potassium channel, voltage gated Shal related subfamily D, member 2	7q31	1(1/0/0)
SP8	Sp8 transcription factor	7p21.2	3(2/0/1)
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	7q21.3	1(1/0/0)
ITGB8	integrin, beta 8	7p15.3	1(1/0/0)
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	7q21	1(1/0/0)
SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	7q21.11	1(1/0/0)
C7orf63	cilia and flagella associated protein 69	7q21.13	0
COL28A1	collagen, type XXVIII, alpha 1	7p21.3	1(1/0/0)
TRRAP	transformation/transcription domain-associated protein	7q21.2-q22.1	1(0/1/0)
IFRD1	interferon-related developmental regulator 1	7q31.1	1(1/0/0)
JAZF1-AS1	JAZF1 antisense RNA 1	7p15.1	1(0/1/0)
NDUFA4	NDUFA4, mitochondrial complex associated	7p21.3	1(0/0/1)
CFAP69	cilia and flagella associated protein 69	7q21.13	1(0/0/1)
NOS3	nitric oxide synthase 3 (endothelial cell)	7q36	2(1/1/0)
PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	7q22	1(0/0/1)
TBXAS1	thromboxane A synthase 1 (platelet)	7q34-q35	1(0/1/0)
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7p12.1	5(2/3/0)
FAM3C	family with sequence similarity 3, member C	7q22.1-q31.1	1(1/0/0)
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	7p22	5(1/2/2)
EPDR1	ependymin related 1	7p14.1	1(1/0/0)
VIPR2	vasoactive intestinal peptide receptor 2	7q36.3	1(1/0/0)
PER4	period circadian clock 3 pseudogene	7p21.3	1(0/0/1)
IL6	interleukin 6	7p21-p15	1(0/1/0)
POU6F2	POU class 6 homeobox 2	7p14.1	1(1/0/0)
CPED1	cadherin-like and PC-esterase domain containing 1	7q31.31	1(0/0/1)
LAMB1	laminin, beta 1	7q22	1(0/0/1)
DGKB	diacylglycerol kinase, beta 90kDa	7p21.2	1(1/0/0)
PVRIG	poliovirus receptor related immunoglobulin domain containing	7q22.1	1(0/0/1)
GRM3	glutamate receptor, metabotropic 3	7q21.1-q21.2	7(3/4/0)
FOXP2	forkhead box P2	7q31	2(0/2/0)
RPA3	replication protein A3, 14kDa	7p21.3	1(1/0/0)
CD36	CD36 molecule (thrombospondin receptor)	7q11.2	3(2/1/0)
BET1	Bet1 golgi vesicular membrane trafficking protein	7q21.1-q22	1(1/0/0)

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Region: chr7:0..159345973 View in gBrowse