BDgene

Gene Report

Basic Info
Approved Symbol CHRM2
Approved Name cholinergic receptor, muscarinic 2
Name Alias acetylcholine receptor, muscarinic 2
Location 7q35-q36
Position chr7:136868669-137020255, 1
External Links HGNC: 1951
Entrez Gene: 1129
Ensembl: ENSG00000181072
UCSC: uc003vtl.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Shi, J., 2007 SNP: rs1364409, rs1455858, rs1824024, rs2061174, rs2350786, rs324614, rs324650, rs4475425, rs6957496, rs7782965, rs7810473, rs8191992, rs978437 no evidence of interaction among these 19 cholinergic genes was found by Allelic Association, Haploview Tests, FITF analysis and FDR correction Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 20)

GO terms by PBA (count: 6)

GO terms by database search (count: 14)


Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 2)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 7)

Related other genetic factors
Gene related SNPs (count: 45)

Literature-origin SNPs (count: 13)

LD-proxies (count: 32)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 2)


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Region: chr7:136868669..137020255 View in gBrowse
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