Gene Report

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Basic Info

Approved Symbol	SNX13
Symbol Alias	RGS-PX1, KIAA0713
Approved Name	sorting nexin 13
Location	7p21.1
Position	chr7:17790761-17940501, -1
External Links	HGNC: 21335 Entrez Gene: 23161 Ensembl: ENSG00000071189 UCSC: uc003stv.3
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Chen, X., 2015		The allele-biased expression of SNX13 in differentiating human neurons was discovered in neuropsychiatric disorders.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0006886	intracellular protein transport	biological process	IMP[11729322]	10
GO:0005769	early endosome	cellular component	IDA[11729322]	13
GO:0043547	positive regulation of GTPase activity	biological process	IDA[11729322]	30
GO:0032266	phosphatidylinositol-3-phosphate binding	molecular function	IDA[25148684]	2
GO:0031901	early endosome membrane	cellular component	IEA	8
GO:0035091	phosphatidylinositol binding	molecular function	IDA[11729322]	5
GO:0038032	termination of G-protein coupled receptor signaling pathway	biological process	IEA	7

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
7p22.2-p21.1	chr7:2800000-20900000	1 (0/0/1)
Chr 7	chr7:0-159345973	3 (0/3/0)
7p21.1	chr7:16500000-20900000	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr7:17790761..17940501 View in gBrowse