BDgene

Gene Report

Basic Info
Approved Symbol GLI3
Previous Symbol GCPS, PHS
Symbol Alias PAP-A, PAPA, PAPA1, PAPB, ACLS, PPDIV
Approved Name GLI family zinc finger 3
Previous Name Greig cephalopolysyndactyly syndrome, "GLI-Kruppel family member GLI3", "glioma-associated oncogene family zinc finger 3"
Name Alias zinc finger protein GLI3, "oncogene GLI3", "DNA-binding protein"
Location 7p13
Position chr7:41960950-42237870, -1
External Links HGNC: 4319
Entrez Gene: 2737
Ensembl: ENSG00000106571
UCSC: uc011kbh.2
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Chen, X., 2015 SNP: rs3735361 GLI3 was implicated in neurological and psychiatric disease Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 82)

GO terms by PBA (count: 4)

GO terms by database search (count: 78)


Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 1)


Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)


Gene related interactors from protein-protein interactions data in HPRD (count: 10)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr7:41960950..42237870 View in gBrowse
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