Gene Report

Basic Info
Approved Symbol PTPRZ1
Previous Symbol PTPZ, PTPRZ
Symbol Alias PTP18, RPTPB, phosphacan
Approved Name protein tyrosine phosphatase, receptor-type, Z polypeptide 1
Location 7q31.3
Position chr7:121873089-122062036, 1
External Links HGNC: 9685
Entrez Gene: 5803
Ensembl: ENSG00000106278
UCSC: uc003vjy.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Chen, X., 2015 PTPRZ1 has been implicated in BPD, SCZ and alcoholism. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 14)

GO terms by PBA (count: 3)

GO terms by database search (count: 11)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 7)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 3)

Gene relationship with MDD

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Region: chr7:121873089..122062036 View in gBrowse
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