Gene Report

Basic Info
Approved Symbol IL6
Previous Symbol IFNB2
Symbol Alias IL-6, BSF2, HGF, HSF
Approved Name interleukin 6
Previous Name interleukin 6 (interferon, beta 2)
Name Alias interferon, beta 2
Location 7p21-p15
Position chr7:22725884-22732002, 1
External Links HGNC: 6018
Entrez Gene: 3569
Ensembl: ENSG00000136244
UCSC: uc003svj.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Clerici, M.,2009 Other variant: IL6_174G/C The distribution of cytokines interleukin (IL)-6 polymorphism was not significantly different in the BD group. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 102)

GO terms by PBA (count: 4)

GO terms by database search (count: 98)

Gene related KEGG pathways (count: 6)

Gene related BioCarta pathways (count: 12)

Gene related interactors from protein-protein interactions data in HPRD (count: 5)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 2)

View in gBrowse

Region: chr7:22725884..22732002 View in gBrowse
View in gBrowse