BDgene

GO Report

Basic Info
ID GO:0007186
Name G-protein coupled receptor signaling pathway
Type biological process
No. of Genes in BDgene  64
Source Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 64)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
CARTPT CART prepropeptide 5q13.2 1(0/1/0) ISS[15908120]
PROK2 prokineticin 2 3p21.1 1(0/1/0) NAS[11259612]
OR4X2 olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene) 11p11.2 1(0/0/1) IBA
TSHR thyroid stimulating hormone receptor 14q24-q31 1(1/0/0) TAS[8552586]
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 7q36.1 2(1/1/0) TAS[7988681]
HCAR2 hydroxycarboxylic acid receptor 2 12q24.31 1(0/1/0) IEA
OR2Y1 olfactory receptor, family 2, subfamily Y, member 1 5q35 1(0/0/1) IEA
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 9q33.2 1(0/1/0) IBA
TAS1R3 taste receptor, type 1, member 3 1p36 1(0/0/1) IC[16720576]
AVPR1B arginine vasopressin receptor 1B 1q32 4(3/1/0) IEA
CHRM1 cholinergic receptor, muscarinic 1 11q12-q13 1(0/1/0) TAS[7925360]
OR3A1 olfactory receptor, family 3, subfamily A, member 1 17p13.3 1(0/0/1) IBA
INS insulin 11p15.5 1(0/1/0) IDA[9092559]
DGKQ diacylglycerol kinase, theta 110kDa 4p16.3 1(0/0/1) IMP[15632189]
ADRA1B adrenoceptor alpha 1B 5q33.3 1(1/0/0) TAS[2154750]
GNA12 guanine nucleotide binding protein (G protein) alpha 12 7p22.3 1(1/0/0) TAS[8290554]
ATRNL1 attractin-like 1 10q26 1(0/1/0) IEA
GPR50 G protein-coupled receptor 50 Xq28 3(2/1/0) IEA
MCHR2 melanin-concentrating hormone receptor 2 6q16 1(1/0/0) IEA
CHRM2 cholinergic receptor, muscarinic 2 7q35-q36 1(0/1/0) TAS[9603968]
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 9q22.1-q22.3 2(0/2/0) TAS[9872316]
FZD3 frizzled class receptor 3 8p21 1(0/1/0) IEA
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3p21.31 1(0/1/0) TAS[8587610]
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 12p13 2(1/1/0) TAS[2107550]
HCAR3 hydroxycarboxylic acid receptor 3 12q24.31 1(0/1/0) IEA
CXCL12 chemokine (C-X-C motif) ligand 12 10q11.1 1(0/0/1) TAS[8752280]
TAAR6 trace amine associated receptor 6 6q23.1 5(4/1/0) TAS[15718104]
NPFFR2 neuropeptide FF receptor 2 4q21 1(0/1/0) TAS[10079187]
GPR124 adhesion G protein-coupled receptor A2 8p11.22 0 IEA
PTGFR prostaglandin F receptor (FP) 1p31.1 1(1/0/0) IEA
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 7p22 1(1/0/0) IEA
APOE apolipoprotein E 19q13.31 1(1/0/0) IDA[16443932]
OXTR oxytocin receptor 3p25 1(0/1/0) IBA
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(1/0/0) TAS[3129724]
ADRA2C adrenoceptor alpha 2C 4p16.3 1(0/1/0) TAS[9371698]
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3q24 1(1/0/0) IBA
ADRA2A adrenoceptor alpha 2A 10q25.2 1(0/1/0) ISS[19965390]
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 5q11.2-q13 3(2/1/0) IMP[22957663]
MCHR1 melanin-concentrating hormone receptor 1 22q13.3 2(1/1/0) TAS[10421368]
CCL2 chemokine (C-C motif) ligand 2 17q11.2-q21.1 3(1/2/0) TAS[10542238]
AGTR1 angiotensin II receptor, type 1 3q24 1(1/0/0) IDA[1378723]
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 6q14-q15 1(0/1/0) TAS[1608964]
SSTR5 somatostatin receptor 5 16p13.3 2(1/1/0) TAS[9892014]
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 5q31-q33 2(1/1/0) TAS[9351641]
TAAR8 trace amine associated receptor 8 6q23.2 1(0/1/0) TAS[15718104]
ADRA1A adrenoceptor alpha 1A 8p21.2 2(0/2/0) TAS[10860850]
FZD2 frizzled class receptor 2 17q21.1 1(0/1/0) IEA
TRHR thyrotropin-releasing hormone receptor 8q23.1 1(0/1/0) IEA
SST somatostatin 3q28 1(0/1/0) TAS[8405411]
BDKRB2 bradykinin receptor B2 14q32.1-q32.2 1(1/0/0) IEA
GPR87 G protein-coupled receptor 87 3q24 1(1/0/0) IBA
ADORA2B adenosine A2b receptor 17p12 1(1/0/0) TAS[7558011]
VIP vasoactive intestinal peptide 6q24-q27 1(1/0/0) TAS[10096039]
OR5AS1 olfactory receptor, family 5, subfamily AS, member 1 11q11 1(0/0/1) IBA
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1q42.2 1(1/0/0) IDA[10406457]
CHRM3 cholinergic receptor, muscarinic 3 1q43 1(0/1/0) TAS[9603968]
RGS7 regulator of G-protein signaling 7 1q43 1(0/1/0) IEA
TAAR1 trace amine associated receptor 1 6q23.1 1(0/1/0) TAS[15718104]
AKT1 v-akt murine thymoma viral oncogene homolog 1 14q32.33 3(3/0/0) TAS[10570282]
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 22q11.2 1(1/0/0) NAS[11072084]
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 1(0/0/1) IDA[12507995]
CMKLR1 chemokine-like receptor 1 12q23.3 1(0/1/0) IDA[14530373]; NAS[9603476]
VIPR2 vasoactive intestinal peptide receptor 2 7q36.3 1(1/0/0) IEA
DRD3 dopamine receptor D3 3q13.3 19(4/15/0) IDA[7911712]