Gene Report

Basic Info
Approved Symbol HCAR2
Previous Symbol GPR109A
Symbol Alias HCA2, HM74A, PUMAG, Puma-g, NIACR1
Approved Name hydroxycarboxylic acid receptor 2
Previous Name G protein-coupled receptor 109A
Name Alias niacin receptor 1
Location 12q24.31
Position chr12:122701293-122703343, -1
External Links HGNC: 24827
Entrez Gene: 338442
Ensembl: ENSG00000182782
UCSC: uc001ucx.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Shink, E.,2005(a) Other variant: HM74a_GC09E01A, HM74a_GC09E01B We found no polymorphisms associated with bipolar disorder in this gene. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 8)

GO terms by PBA (count: 2)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 6)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr12:122701293..122703343 View in gBrowse
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