Gene Report

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Basic Info

Approved Symbol	OR3A1
Symbol Alias	OLFRA03, OR40, OR17-40
Approved Name	olfactory receptor, family 3, subfamily A, member 1
Location	17p13.3
Position	chr17:3291635-3292600, -1
External Links	HGNC: 8282 Entrez Gene: 4994 Ensembl: ENSG00000180090 UCSC: uc002fvh.1
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Georgi, B., 2014	SNP: rs149826123	Amish-specific putative damaging exonic missense variant was found within this gene.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IBA	219
GO:0005886	plasma membrane	cellular component	TAS	360

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0004930	G-protein coupled receptor activity	molecular function	IEA	26
GO:0007186	G-protein coupled receptor signaling pathway	biological process	IBA	64
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	biological process	IBA	5
GO:0007165	signal transduction	biological process	NAS[8921386]	136
GO:0004984	olfactory receptor activity	molecular function	IBA	5

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in BDgene	Brief Description
hsa04740	Olfactory transduction	11

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs149826123	chr17:3292483 - 3292483(1)	intron_variant; missense_variant; non_coding_transcript_variant	1(0/0/1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
17p13	chr17:0-10800000	3 (0/3/0)
Chr 17	chr17:0-83257441	3 (0/3/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr17:3291635..3292600 View in gBrowse